复方积雪草合剂治疗早期糖尿病肾病患者的临床疗效观察

发布时间：2018-06-21 12:34

本文选题：复方积雪草合剂 + 糖尿病肾病　；参考：《浙江中医药大学》2017年硕士论文

【摘要】：目的探讨复方积雪草合剂在西药基础治疗上对早期2型糖尿病肾病患者肾保护作用。方法按实验入组标准纳入的60例早期糖尿病肾病的患者,随机分为实验组和对照组,研究时间为3个月。两组均采用一般治疗(饮食、运动控制、戒烟)、降压、降糖、降脂等基础治疗,实验组加用复方积雪草合剂。3个月后对两组患者的尿微量白蛋白/尿肌酐、尿常规、血清肌酐、尿素氮、血糖、尿酸以及中医症状评分等指标进行观察和比较。结果实验组的尿微量白蛋白、尿微量白蛋白/肌酐值、血清肌酐等指标下降明显优于对照组,差异有统计学意义(p0.05)。结论复方积雪草合剂用于治疗早期糖尿病肾病,能够明显的降低尿微量白蛋白排泄率,对早期糖尿病肾病有良好的临床疗效。
[Abstract]:Objective to investigate the protective effect of compound asiatica mixture on the kidney of early type 2 diabetic nephropathy patients in the basic treatment of western medicine. Methods 60 patients with early diabetic nephropathy were randomly divided into experimental group and control group for 3 months. Both groups were treated with general treatment (diet, exercise control, smoking cessation, hypotension, hypoglycemia, lipid-lowering and so on. The experimental group was treated with compound Centella asiatica mixture. After 3 months, urine microalbumin / creatinine, urine routine, serum creatinine were used in both groups. Urea nitrogen, blood glucose, uric acid and TCM symptom score were observed and compared. Results the levels of urinary microalbumin, urinary microalbumin / creatinine and serum creatinine in the experimental group were significantly lower than those in the control group (P 0.05). Conclusion the treatment of early diabetic nephropathy with compound Xuehue mixture can obviously reduce the excretion rate of urinary microalbumin and has a good clinical effect on early diabetic nephropathy.
【学位授予单位】：浙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.5;R259

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