ERCP术后胰腺炎与高淀粉酶血症相关危险因素的分析

发布时间：2018-09-03 15:52

【摘要】：目的:探讨内镜下逆行胰胆管造影术(Endoscopic retrograde cholangiopancreatography,ERCP)所致的常见并发症术后胰腺炎(Post-ERCP Pancreatitis,PEP)和高淀粉酶血症(Hyperamylasemia)临床危险因素。方法:对2014年1月—2016年10月于广西医科大学第一附属医院行ERCP且符合纳入标准的共919例行回顾性分析,筛选出8种因素进行X~2检验及Logistics回归分析。结果:本文研究纳入病例共919例,其中正常组病人722例,PEP组44例,发生率为4.79%(44/919);术后高淀粉酶血症组153例,发生率为16.64%(153/919)。PEP的单因素分析得出的危险因素为:行EST、ENBD、EPBD术、既往有胰腺炎病史;多因素分析得出的危险因素为:既往有胰腺炎病史。术后高淀粉酶血症的单因素分析得出危险因素为:存在EST、EPBD、既往有胰腺炎病史;多因素分析得出危险因素为:男性、存在EST、EPBD、胆总管支架植入术、既往有胰腺炎史。结论:1.PEP的危险因素为:有胰腺炎病史;2.ERCP术后高淀粉酶血症的危险因素为:男性、有胰腺炎病史、行EST、行EPBD、行胆总管支架植入术。
[Abstract]:Objective: to investigate the clinical risk factors of postoperative pancreatitis (Post-ERCP Pancreatitis,PEP) and hyperamylase (Hyperamylasemia) induced by endoscopic retrograde cholangiopancreatography (Endoscopic retrograde cholangiopancreatography,ERCP). Methods: a total of 919 cases of ERCP from January 2014 to October 2016 in the first affiliated Hospital of Guangxi Medical University were retrospectively analyzed and 8 factors were selected for Xan2 test and Logistics regression analysis. Results: a total of 919 cases were included in this study, of which 44 cases (4.79%) were in normal group and 153 cases in hyperamylase group (16.64% (153 / 919). The risk factors were as follows: EST,ENBD,EPBD was performed. The previous history of pancreatitis and the risk factors of multivariate analysis were as follows: previous history of pancreatitis. Univariate analysis of postoperative hyperamylase showed that EST,EPBD, had a history of pancreatitis in the past, and multivariate analysis showed that the risk factors were: male, EST,EPBD, common bile duct stent implantation, and history of pancreatitis. Conclusions 1. The risk factors of PEP were as follows: having history of pancreatitis. 2. The risk factors of hyperamylase after ERCP were: male, history of pancreatitis, EST, with EPBD, and common bile duct stent implantation.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R576

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