363例慢性前列腺炎与勃起功能障碍的相关性研究
发布时间：2019-02-15 04:01
【摘要】：目的:通过对363例慢性前列腺炎(CP)患者的中医证型以及合并勃起功能障碍(ED)的情况,探索慢性前列腺炎在中医证型上与勃起功能障碍之间的相关研究,为慢性前列腺炎的辨证论治提供临床指导意义。方法:将在2015年10月一2017年2月门诊就诊的363例CP患者,通过国际前列腺炎症状评分表(NIH-CPSI);国际前列腺症状评分(IPSS):下尿路症状评价;国际勃起功能简化量表(IIEF-5)及慢性前列腺炎中医证型量表调查慢性前列腺炎患者NIH-CPSI评分、IPSS评分、勃起功能障碍及中医证型情况,分析慢性前列腺炎患者中医证型与勃起功能障碍之间的相关性。结果:(1)CP患者总体中医证型以复合证型为主,复合证型301例,约占82.92%,并且复合证型中又以湿热下注型合并气滞血瘀型多见,182例,占50.14%。单一证型62例,约占17.08%。(2)363例慢性前列腺炎患者前列腺炎症状的严重程度(NIH-CPSI评分)与勃起功能障碍的严重程度(IIEF-5评分)比较P0.05,有统计学意义。慢性前列腺炎患者ED的患病率随着前列腺炎下尿路症状的严重程度而有逐渐升高的趋势。说明慢性前列腺炎下尿路症状的严重程度可能与ED的患病有一定关系。(3)182例湿热下注合并气滞血瘀型患者合并勃起功能障碍者有79例;119例其他复合证型患者合并勃起功能障碍者有35例;62例单一证型患者合并勃起功能障碍有24例。根据所分3种不同证型合并ED的发生情况,经比较χ2=6.435,P=0.05,差异有统计学意义。按照IIEF-5评分将慢性前列腺炎伴有勃起功能障碍患者分为轻度及中重度ED进行比较经比较χ2 =6.435,P=0.04差异有统计学意义。3种证型中NIH-CPSI评分与IIEF-5评分之间呈负相关(湿热下注合并气滞血瘀型:r=-0.429,P0.001,其他复合证型:r=-0.406,P0.001,单一证型:r=-0.458,P0.001,总体:r=-0.422,P0.001)。IPSS评分和IIEF-5评分之间呈负相关(湿热下注合并气滞血瘀型:r=-0.171,PO.001,其他复合证型:r=-0.307,P0.001,单一证型:r=-0.446,P0.001,总体:r=-0.279,P0.001)。结论:本次调查,湿热下注合并气滞血瘀型是CP患者的主要的中医证型。慢性前列腺炎在症状的严重程度上与ED有相关性。CP患者,其下尿路症状的严重程度与ED的发生具有相关性。CP患者中医证型与ED的发生有一定相关性,可能是ED诱发因素,也有可能是其病机基础。
[Abstract]:Objective: to investigate the relationship between chronic prostatitis and erectile dysfunction (ED) in patients with chronic prostatitis (CP). To provide clinical guidance for the treatment of chronic prostatitis based on syndrome differentiation. Methods: a total of 363 patients with CP from October to February 2017 were enrolled in this study through the International Prostatitis symptom scale (NIH-CPSI), the International Prostate symptom scale (IPSS):) and the urinary tract symptom Assessment (IPSS):). International simplified erectile function scale (IIEF-5) and TCM Syndrome scale for chronic Prostatitis NIH-CPSI score, IPSS score, erectile dysfunction and TCM Syndromes in patients with chronic Prostatitis were investigated. To analyze the correlation between TCM syndromes and erectile dysfunction in patients with chronic prostatitis. Results: (1) the main types of TCM syndromes in patients with CP were compound syndrome type, 301 cases (82.922), and the type of damp-heat injection combined with Qi stagnation and blood stasis was more common in the complex syndrome type, 182 cases (50.14%). (2) the severity of prostatitis symptoms (NIH-CPSI score) in 363 patients with chronic prostatitis was significantly higher than that in erectile dysfunction (IIEF-5 score) (P 0.05). The prevalence of ED in patients with chronic prostatitis tends to increase with the severity of lower urinary tract symptoms of prostatitis. It is suggested that the severity of lower urinary tract symptoms of chronic prostatitis may be related to the prevalence of ED. (3) there were 79 cases with erectile dysfunction in 182 patients with dampness and heat betting combined with Qi stagnation and blood stasis. There were 35 patients with erectile dysfunction and 24 patients with erectile dysfunction in 62 patients with single syndrome. According to the occurrence of ED in three different syndromes, the difference was statistically significant. According to the IIEF-5 score, the patients with chronic prostatitis with erectile dysfunction were divided into mild and moderate to severe ED. There was a negative correlation between the NIH-CPSI score and the IIEF-5 score in the three syndromes (Wet and Heat betting combined with Qi stagnation and Blood stasis: rhi-0.429, P0.001, other syndrome types: rhi-0.406, P0.001, P 0.001, P 0.001). Single syndrome type: r-0.458U P0.001. overall: r-0.422P0.001). IPSS score and IIEF-5 score were negatively correlated (damp-heat betting combined with Qi stagnation and blood stasis type: rhi-0.171 P0.001, P 0.001, P 0.001). Other complex syndromes were r-0.307 (P0.001), single type: r-0.446N P0.001, total: r-0.279 (P0.001). Conclusion: in this investigation, damp-heat betting combined with Qi stagnation and blood stasis is the main TCM syndrome of CP patients. The severity of chronic prostatitis is related to ED. In CP patients, the severity of lower urinary tract symptoms is correlated with the occurrence of ED. There is a certain correlation between TCM syndromes of CP patients and the occurrence of ED, which may be the inducing factor of ED. It may also be the basis of its pathogenesis.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.5
本文编号：2422944
[Abstract]:Objective: to investigate the relationship between chronic prostatitis and erectile dysfunction (ED) in patients with chronic prostatitis (CP). To provide clinical guidance for the treatment of chronic prostatitis based on syndrome differentiation. Methods: a total of 363 patients with CP from October to February 2017 were enrolled in this study through the International Prostatitis symptom scale (NIH-CPSI), the International Prostate symptom scale (IPSS):) and the urinary tract symptom Assessment (IPSS):). International simplified erectile function scale (IIEF-5) and TCM Syndrome scale for chronic Prostatitis NIH-CPSI score, IPSS score, erectile dysfunction and TCM Syndromes in patients with chronic Prostatitis were investigated. To analyze the correlation between TCM syndromes and erectile dysfunction in patients with chronic prostatitis. Results: (1) the main types of TCM syndromes in patients with CP were compound syndrome type, 301 cases (82.922), and the type of damp-heat injection combined with Qi stagnation and blood stasis was more common in the complex syndrome type, 182 cases (50.14%). (2) the severity of prostatitis symptoms (NIH-CPSI score) in 363 patients with chronic prostatitis was significantly higher than that in erectile dysfunction (IIEF-5 score) (P 0.05). The prevalence of ED in patients with chronic prostatitis tends to increase with the severity of lower urinary tract symptoms of prostatitis. It is suggested that the severity of lower urinary tract symptoms of chronic prostatitis may be related to the prevalence of ED. (3) there were 79 cases with erectile dysfunction in 182 patients with dampness and heat betting combined with Qi stagnation and blood stasis. There were 35 patients with erectile dysfunction and 24 patients with erectile dysfunction in 62 patients with single syndrome. According to the occurrence of ED in three different syndromes, the difference was statistically significant. According to the IIEF-5 score, the patients with chronic prostatitis with erectile dysfunction were divided into mild and moderate to severe ED. There was a negative correlation between the NIH-CPSI score and the IIEF-5 score in the three syndromes (Wet and Heat betting combined with Qi stagnation and Blood stasis: rhi-0.429, P0.001, other syndrome types: rhi-0.406, P0.001, P 0.001, P 0.001). Single syndrome type: r-0.458U P0.001. overall: r-0.422P0.001). IPSS score and IIEF-5 score were negatively correlated (damp-heat betting combined with Qi stagnation and blood stasis type: rhi-0.171 P0.001, P 0.001, P 0.001). Other complex syndromes were r-0.307 (P0.001), single type: r-0.446N P0.001, total: r-0.279 (P0.001). Conclusion: in this investigation, damp-heat betting combined with Qi stagnation and blood stasis is the main TCM syndrome of CP patients. The severity of chronic prostatitis is related to ED. In CP patients, the severity of lower urinary tract symptoms is correlated with the occurrence of ED. There is a certain correlation between TCM syndromes of CP patients and the occurrence of ED, which may be the inducing factor of ED. It may also be the basis of its pathogenesis.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R277.5
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