CP对RHD患者慢性充血性心力衰竭的临床疗效观察

发布时间：2016-11-09 16:42

To observe the clinical effect of CP on RHD in patients with chronic congestive heart failure
[Abstract]Objective: Discussion clinical efficacy of phosphocreatine (CP) for the treatment of rheumatic heart disease (RHD) in patients with chronic congestive heart failure.Methods: From 2013 March to 2014 April in our hospital treatment of rheumatic heart disease patients with chronic congestive heart failure,were randomly divided into control group of 60 cases and 60 cases in experimental group, observe two groups before and after treatment cardiac function，6 minutes walking distance and LVEF, etc. Results: The observation group after treatment, heart function improved with a total effective rate of 91.67%, significantly higher than the control group 75.00%; Observation group and control group after treatment LVEF, SV, LVDD and CO indexes than before treatment were improved (p < 0.05), but the observation group after treatment, LVEF, SV, LVDD and CO is better than the control group after treatment (P < 0.05) ; After the treatment, the observation group of 6 minutes walking distance to the (352.67±47.68) m was longer than that in the control group (294.37±42.31) m, the difference was statistically significant (P < 0.05).Conclusion: Creatine phosphate (CP) has better clinical efficacy in treating patients rheumatic heart disease (RHD) with chronic congestive heart failure, it is worth in clinical promotion
[Keywords] phosphocreatine; rheumatic heart disease; chronic congestive heart failure; Clinical observation

心力衰竭主要是指在静脉血流正常情况下，由原发心脏损害所导致的心排血量减少，而不能够满足患者组织代谢所需要的综合性症状。慢性充血性心力衰竭(congestive heart failure,CHF)是器官性心脏病的终末阶段，也是风心病(Rheumatic heart disease,RHD)的临床综合征[1]。传统治疗方案为纠正患者心衰与抗心律，临床疗效有限。运用磷酸肌酸治疗，在心肌能量储备方面具有较大改善，可以有效改善患者心脏缺血部位的血液循环，加强保护心肌[2]。为分析磷酸肌酸对RHD患者CHF的治疗疗效与安全性，，我院选择了2013年3月至2014年4月间的120例风心病慢性充血性心力衰竭患者进行了以下研究。

1资料与方法
1.1一般资料
1.2治疗方法
1.3观察指标
1.4统计学处理
2结果
2.1 两组患者心功能改善情况
2.2两组患者LVEF、SV等情况
2.3两组6分钟步行试验情况
3.讨论

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本文编号：169316