室内装修污染对异常妊娠结局影响病例对照研究

发布时间：2018-04-14 06:37

本文选题：室内装修污染 + 异常妊娠　；参考：《环境卫生学杂志》2013年01期

【摘要】：目的探讨室内装修污染与异常妊娠结局之间的关系。方法应用1∶1匹配的病例对照研究方法,调查在北京协和医院就诊的200名异常妊娠孕妇(病例组)及与其年龄相匹配(±2岁)的正常妊娠产妇(对照组),应用多因素条件Logistic逐步回归进行分析。结果病例组中孕期或怀孕之前半年内家中或工作单位使用有挥发性气味材料进行过装修的比例(32.0%)显著高于对照组(20.5%,χ2=6.81,P=0.009)。病例组自述有装修异味的时间(P50=3个月)显著高于对照组(P50=1个月,H=6.67,P=0.010)。以未进行过装修作为参照,有装修异味的时间≤3和3个月的相对危险度分别为1.25和5.41(趋势性χ2=10.86,P=0.001)。在调整了其他危险因素的作用之后,室内有装修异味的时间在3个月以上时可能显著增加孕妇发生异常妊娠的相对危险度(OR=13.36,95%CI:1.27～140.19)。结论室内装修污染可能是孕妇发生异常妊娠的危险因素,且两者之间可能存在剂量—反应关系。
[Abstract]:Objective to explore the relationship between indoor decoration pollution and abnormal pregnancy outcomes between 1. Methods: 1 matched case-control study, survey in Peking Union Medical College Hospital from 200 abnormal pregnant women (case group) and age-matched controls (+ 2 years) of the normal pregnant women (control group), the application of multivariate stepwise Logistic regression analysis. Results in the case group during pregnancy or pregnancy within half a year before the home or work units to use a volatile material decoration proportion (32%) was significantly higher than the control group (20.5%, X 2=6.81, P=0.009). The case group reported decoration smell time (P50=3 months) was significantly higher than the control group (P50=1 month, H=6.67, P=0.010). With no decoration decoration smell as a reference, time less than a relative risk of 3 and 3 months were 1.25 and 5.41 (trend P x 2=10.86, =0.001) after adjusting for other risk. After the role of indoor decoration smell time could significantly increase the relative risk of abnormal pregnancy pregnant women in more than 3 months (OR=13.36,95%CI:1.27 ~ 140.19). Conclusion the indoor decoration pollution may be a risk factor for abnormal pregnancy in pregnant women, there may be a dose - response relationship and between the two.

【作者单位】：中国疾病预防控制中心环境与健康相关产品安全所环境流行病与健康影响室;北京协和医院产科;
【基金】：中国疾病预防控制中心环境与健康相关产品安全所中青年科学基金资助项目
【分类号】：R714.2

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