热刺激取出骨结合种植体动物模型的建立

发布时间：2018-03-22 18:30

  本文选题：牙种植体　切入点：骨结合　出处：《口腔医学研究》2017年07期 　论文类型：期刊论文

【摘要】：目的:研究热刺激取出骨结合牙种植体的条件,建立热刺激微创取出骨结合牙种植体的动物模型。方法:选用4只1~2岁杂种犬为实验动物,拔除双侧下颌第三或第四前磨牙,2个月后常规植入牙种植体,3个月后经临床及放射学检查,确定骨结合形成,随机选取右侧为实验侧,组成实验组,分别以(48±1)℃持续1min(简称A因素)、(53±1)℃持续2.5min(B)、(59±1)℃持续3.5min(C)刺激实验侧种植体,于每次热刺激前及刺激后4周测量种植体稳定性系数(ISQ),改良菌斑指数(modified plaque index,mPLI),探诊深度(probing depth,PD),观察影像学表现以及能否用扭矩扳手取出种植体,左侧为对照侧,组成对照组,不施加任何热刺激,测量项目同实验组。采用SPSS22.0统计软件对实验数据进行统计分析。结果:A、B因素刺激前和刺激后4周,实验组与对照组相比,ISQ、mPLI,PD无显著性差异,影像学无明显变化,无法用扭矩扳手取出种植体。C因素刺激后4周与对照组相比,实验组ISQ明显下降,差异具有显著性(P0.05),根尖X片显示种植体周围出现线形低密度影,低密度影外侧骨密度略有增高,但mPLI,PD实验组和对照组无显著性差异,实验组采用50Ncm的扭矩可以取出种植体,对照组无法取出。种植体取出术后2个月,实验组牙槽骨基本愈合,与取出术前相比,牙槽嵴宽度和高度无显著性变化。结论:动物实验显示,已完成骨结合的种植体在(59±1)℃持续3.5 min热刺激条件下可使其周围骨质出现有限破坏,从而破坏其骨结合,达到微创取出种植体的目的,成功建立了热刺激取出骨结合牙种植体动物模型。
[Abstract]:Objective: to study the condition of extraction of osseous and dental implants by thermal stimulation, and to establish an animal model of osseous and dental implants taken out by thermal stimulation. Methods: four mongrel dogs aged 1 or 2 years were selected as experimental animals. Bilateral mandibular third or fourth premolars were extracted and implanted into dental implants 2 months later. After 3 months clinical and radiologic examinations were performed to determine the formation of bone union. The right side was randomly selected as the experimental side to form the experimental group. The experimental implants were stimulated at 48 卤1 鈩，

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