基于fNIRS的情绪对工作记忆负荷影响规律研究

发布时间：2018-04-11 16:28

本文选题：功能性近红外光谱技术 + 血氧特性　；参考：《航天医学与医学工程》2017年02期

【摘要】：目的研究情绪刺激和任务负荷共同影响下的大脑皮层血氧特性响应规律。方法 20名年轻男性分别进行了负性、中性与积极3种情绪图片刺激下1~3-back认知记忆负荷任务实验,采用功能近红外谱(functional near-infrared spectroscopy,fNIRS)监测参试者脑前额叶皮层(prefrontal cortex,PFC)功能区和左右运动区的含氧血红蛋白(Hb O_2)与脱氧血红蛋白(Hbr)信号均值、斜率及近似熵(approximate entropy,ApEn)3种生理特征指标来描述其脑功能活动。结果随着任务负荷增加,均值表征的脑功能活动强度增强,PFC区域血氧供应和脑功能活动强度变化率降低且趋于稳定。近似熵用于表征的脑功能活动复杂度指标,随着任务负荷增加,中性情绪状态下复杂度降低,而在负性和积极情绪状态下复杂度上升。结论背外侧PFC区域为任务负荷敏感区域脑区;运动区域脑功能活动会受情绪状态影响。近似熵能有效地表征脑区fNIRS信号的复杂度变化,并适合描述情绪状态下大脑皮层功能活动多样性。
[Abstract]:Objective to study the response of cerebral cortex blood oxygen characteristics under the influence of emotional stimulation and task load.Methods 20 young men were tested with 1~3-back cognitive memory load task stimulated by negative, neutral and positive emotional images.Functional near infrared spectroscopy (near-infrared) was used to monitor the mean values of hemoglobin (HB) and deoxyhemoglobin (HBR) signals in the prefrontal cortex of the prefrontal cortex and the left and right motor regions of the subjects.The slope and approximate entropy were used to describe the brain function.Results with the increase of task load, the change rate of blood oxygen supply and the intensity of brain function activity decreased and tended to be stable.Approximate entropy is used to characterize the complexity of brain function. With the increase of task load, the complexity decreases in neutral emotional state, but increases in negative and positive emotional state.Conclusion the dorsolateral PFC area is the task load sensitive area, and the brain function in motor area is affected by emotional state.Approximate entropy can effectively characterize the complexity of fNIRS signals in the brain region and is suitable for describing the diversity of cerebral cortex function in emotional state.
【作者单位】：中国航天员科研训练中心人因工程重点实验室;
【基金】：国家自然科学基金青年基金(71201148) 人因工程重点实验室课题(9140C770208150C77320,2012SY54B1701,SYFD150051805)
【分类号】：R338

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