人参茎叶提取物对Ⅰ型糖尿病小鼠模型的影响
发布时间：2019-07-17 21:01
【摘要】：为研究人参茎叶提取物对Ⅰ型糖尿病的影响,选取40只清洁级雄性昆明小鼠以剂量120 mg/kg·体重腹腔注射链脲佐菌素(STZ)建立Ⅰ型糖尿病小鼠模型,试验期间定时检测小鼠体重及空腹血糖值,试验20d后眼球取血处理得血清,测定小鼠血清总胆固醇(TC)、甘油三酯(TG)、超氧化物歧化酶(SOD)及丙二醛(MDA)含量并进行分析。结果显示,一定剂量的人参茎叶提取物悬浊液有助于改善Ⅰ型糖尿病小鼠的抗氧化能力,降低血清血脂水平,对缓解糖尿病并发症有重要意义。
[Abstract]:In order to study the effect of ginseng stem and leaf extract on type I diabetes mellitus, 40 clean male Kunming mice were intraperitoneally injected with streptozotocin (STZ) at a dose of 120 mg/kg. The body weight and fasting blood glucose value of mice were measured regularly during the experiment. After 20 days of experiment, the serum was taken from eyeball to obtain serum total cholesterol (TC), TG (TG),. The contents of (SOD) and (MDA) in SOD were analyzed. The results showed that a certain dose of ginseng stem and leaf extract suspension was helpful to improve the antioxidant capacity of type I diabetic mice and reduce the level of serum lipid, which was of great significance to alleviate the complications of diabetes mellitus.
【作者单位】： 长白山生物资源与功能分子教育部重点实验室;延边大学农学院;四川省原子能研究院;
【基金】：辐照保藏四川省重点实验室开放课题项目(编号:SCFZBC2017003)
【分类号】：R285.5;R-332
本文编号：2515634
[Abstract]:In order to study the effect of ginseng stem and leaf extract on type I diabetes mellitus, 40 clean male Kunming mice were intraperitoneally injected with streptozotocin (STZ) at a dose of 120 mg/kg. The body weight and fasting blood glucose value of mice were measured regularly during the experiment. After 20 days of experiment, the serum was taken from eyeball to obtain serum total cholesterol (TC), TG (TG),. The contents of (SOD) and (MDA) in SOD were analyzed. The results showed that a certain dose of ginseng stem and leaf extract suspension was helpful to improve the antioxidant capacity of type I diabetic mice and reduce the level of serum lipid, which was of great significance to alleviate the complications of diabetes mellitus.
【作者单位】： 长白山生物资源与功能分子教育部重点实验室;延边大学农学院;四川省原子能研究院;
【基金】：辐照保藏四川省重点实验室开放课题项目(编号:SCFZBC2017003)
【分类号】：R285.5;R-332
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1 赵玉敏,许智军,宫汝淳;人参茎叶提取物对蟾蜍心肌活动的影响[J];人参研究;2002年03期
，本文编号：2515634
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