基于3D人脸数据库的儿童面部发育评估

发布时间：2018-01-01 18:15

本文关键词：基于3D人脸数据库的儿童面部发育评估　出处：《中国生物医学工程学报》2014年05期 　论文类型：期刊论文

【摘要】：研究发现,患有遗传性疾病的人脸常伴有面部发育异常的问题,如患有威廉姆斯综合征(WS)和唐氏综合征(DS)的人脸。为此,对儿童面部发育的研究有助于遗传性疾病的早筛查与早诊断。基于目前国内还没有儿童3D人脸数据库的现状,通过3dMDface人脸采集系统,采集人脸5 600例,对原始数据进行预处理使人脸稠密对应,从而构建3D人脸数据库。利用人体测量学标定面部各器官的关键点,建立标准测量指标,建立儿童面部发育评估系统。其中,对浙江地区分别患有DS的人脸55例和患有WS的人脸30例的19项测量指标与正常人脸比较分析。结果发现,DS人脸两眼内宽分布在第90百分位以上的样本为76.3%,鼻长分布在第10百分位以下的样本为61.8%,耳长分布在第10百分位以下的样本为87.2%,上面深分布在第10百分位以下的样本为89%,颅面变异指数为1.630~2.117,T检验分析为T=10.130,P=.000;WS人脸鼻宽与口裂宽分布在第75百分位以上的样本分别为50%和66.7%,而两耳屏间宽分布在第25百分位以下的样本为63.3%,颅面变异指数为1.714~2.365,T检验分析为T=12.213,P=.000。这表明,该两种特殊人脸与正常人脸差异具有明显的统计学意义。因此,利用该评估系统能正确反映患有遗传性疾病特殊人脸的显著性特征,基于3D人脸数据库建立的面部发育评估系统对儿童生长发育及面部异常的评价具有临床应用价值。
[Abstract]:Studies have found that faces with inherited diseases are often associated with facial dysplasia, such as those with Williams' syndrome (WS) and Down's syndrome (DSV). The research on facial development of children is helpful to the early screening and diagnosis of genetic diseases. Based on the fact that there is no 3D face database for children in China, 3D MDface face acquisition system is adopted. In order to construct 3D face database, 5 600 face samples were collected and processed to make the human face dense. The key points of facial organs were calibrated by anthropometry, and the standard measurement indexes were established. To establish the evaluation system of children's facial development. The 19 indexes of 55 face cases with DS and 30 cases with WS face in Zhejiang area were compared with the normal faces. The results showed that: 1. 76.3% of the eyes of DS face were above the 90th percentile, and 61.8% of the nose length were below the 10th percentile. The ear length distribution below 10th percentile was 87.2 and the upper depth below 10th percentile was 89. The craniofacial variation index was 1.630 and 2.117. The analysis of T test was: TX 10.130 Pu. 000; The samples of WS with nose width and mouth fissure width above 75th percentile were 50% and 66.7, respectively, while 63.3% samples with width between the two ears under 25th percentile. The craniofacial variation index was 1.714 and 2.365 T test. The difference between these two special faces and normal faces is statistically significant. Therefore, the evaluation system can accurately reflect the salient features of special faces with hereditary diseases. The evaluation system of facial development based on 3D face database is of clinical value for the evaluation of children's growth and development and facial abnormalities.
【作者单位】：浙江大学医学院附属儿童医院;
【基金】：浙江省重点科技创新团队(2010R50045)
【分类号】：R322;TP391.41
【正文快照】： 引言早期对于人脸的研究主要集中在二维图像上。由于二维人脸图像受到姿态、光照等影响,因此其分析性能会降低。而3D人脸模型在三维信息分析方面具有很大优势,因为三维数据不受光照、角度和姿态变化的影响[1]。建立3D人脸数据库,尤其是具有纹理贴图的3D人脸数据库,是人脸方面

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