医学遗传咨询和出生缺陷干预相关问题探讨

发布时间：2018-03-02 01:10

本文关键词： 医学遗传咨询出生缺陷干预遗传检测　出处：《生物技术世界》2014年12期 　论文类型：期刊论文

【摘要】：目的:研究分析科学有效的医学遗传咨询服务对出生缺陷干预所产生的影响效果,意在降低我国出生缺陷人口率。方法:回顾性分析2010年6月~2014年6月期间(其中2010年6月~2012年6月期间为第一干预阶段,该干预阶段给予常规出生缺陷干预服务;2013年7月~2014年6月为第二干预阶段,该干预阶段给予优质医学遗传咨询以及针对性出生缺陷干预服务)本院两个阶段产生的出生缺陷事件的具体原因,并且依照这些出生缺陷原因探讨出有效干预对策。结果:第一干预阶段出现了60例出生缺陷事件,60例出生缺陷事件中有30例是由于遗传因素引起的,占出生缺陷事件总例数的50.00%;10例出生缺陷事件是由于环境因素引起的,占出生缺陷事件总例数的16.66%;由于药物因素引起的出生缺陷为6例,占出生缺陷事件总例数的10.00%;由于心理因素引起的出生缺陷为4例,占出生缺陷事件总例数的6.66%。第二干预阶段中出现了10例出生缺陷事件,两组出生缺陷事件发生率进行组间对比具有显著差异,P0.05,差异具有统计学意义。结论:在我国出生缺陷干预的实践过程当中,遗传咨询服务,例如说婚前筛查、孕前筛查以及产前筛查的有效实施均在减少我国缺陷人口出生率的方面起到了不可替代的重要作用。
[Abstract]:Objective: to study and analyze the effect of scientific and effective medical genetic counseling service on birth defect intervention. Methods: the period from June 2010 to June 2014 was analyzed retrospectively. Routine birth defect intervention was given in the intervention stage, and the second intervention stage was from July 2013 to June 2014. The specific causes of birth defect events in the two stages of our hospital were given quality medical genetic counseling and targeted birth defect intervention services. According to the causes of birth defects, the effective intervention countermeasures were discussed. Results: in the first intervention stage, there were 60 cases of birth defects and 60 cases of birth defects. 30 of the 60 cases of birth defects were caused by genetic factors. Ten cases of birth defects were caused by environmental factors and accounted for 16.66 cases of the total number of birth defect events, and 6 cases were due to drug factors. 10.00% of the total number of birth defect events; 4 cases of birth defects caused by psychological factors, 6.66% of the total number of birth defect events. 10 cases of birth defects occurred in the second intervention stage. There was significant difference in the incidence of birth defect events between the two groups (P 0.05). Conclusion: in the practice of birth defect intervention in China, genetic counseling services, such as pre-marital screening, Pre-pregnancy screening and antenatal screening have played an irreplaceable role in reducing the birth rate of defective population in China.
【作者单位】：承德医学院;
【分类号】：R394

【参考文献】