神经外科与非神经外科患者感染肠杆菌科细菌分布与耐药性分析

发布时间：2018-05-02 16:05

本文选题：肠杆菌科细菌 + 神经外科　；参考：《中华医院感染学杂志》2014年21期

【摘要】：目的观察神经外科与非神经外科患者肠杆菌科细菌感染耐药差异,为临床提供参考。方法于2011年6月-2014年4月从外科系统住院患者中分离出721株肠杆菌科细菌,其中181株来自神经外科,540株来自非神经外科,采用法国生物梅里埃公司VITEK-32细菌鉴定仪进行细菌鉴定,并进行比较分析。结果肠杆菌科细菌对亚胺培南、头孢哌酮/舒巴坦、美罗培南、哌拉西林/他唑巴坦等抗菌药物的耐药率较低,分别为0.28%、8.32%、0.42%、9.15%;对阿米卡星、头孢哌酮/舒巴坦、头孢吡肟、美罗培南、左氧氟沙星等抗菌药物耐药率神经外科与非神经外科分别为19.50%与11.89%、14.67%与6.18%、47.51%与30.24%、1.45%与0、50.74%与38.95%,差异有统计学意义(P0.05)。结论外科感染肠杆菌科细菌的耐药快速上升,尤以神经外科严重。
[Abstract]:Objective to observe the difference of drug resistance between neurosurgery and non-neurosurgery patients with Enterobacteriaceae infection. Methods from June 2011 to April 2014, 721 strains of Enterobacteriaceae were isolated from patients hospitalized in the surgical system, of which 181 were from neurosurgery and 540 were from non-neurosurgery. The bacteria were identified by the VITEK-32 bacteria identification instrument of Bio-Meridier of France. And carries on the comparative analysis. Results the resistance rates of Enterobacteriaceae to imipenem, cefoperazone / sulbactam, meropenem, piperacillin / tazobactam were low, 0.280.320.42 and 9.15.The drug resistance rates of amikacin, cefoperazone / sulbactam, cefepime, cefoperazone / sulbactam, cefepime, etc. The antimicrobial resistance rates of meropenem and levofloxacin were 19.50% and 11.89% in neurosurgery and 14.67% and 6.18% respectively in neurosurgery and non-neurosurgery. The difference was statistically significant (P 0.05). Conclusion the drug resistance of enterobacteriaceae in surgical infection is increasing rapidly, especially in neurosurgery.
【作者单位】：贵阳医学院第三附属医院医院感染管理科;贵阳医学院第三附属医院检验科;
【基金】：贵州省科技厅基金资助项目(黔科合LG字[2012]077) 贵州省黔南州科技基金资助项目(黔南科合社字[2013]20)
【分类号】：R378.2

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