睾酮诱导骨髓巨噬细胞凋亡并增加杜氏利什曼原虫对巨噬细胞的侵袭力

发布时间：2021-02-07 07:43

　　Sexual dimorphism in the immune systems of females and males is well established. The sex-dependent differences between female and male normal and autoimmune responses is generally attributed to the influence of estrogens and androgens even though limited information has been reported on the specific mechanisms of steroids on immune cells. In general terms females have a greater resistance to various bacterial and viral infections than males with their other enhanced immune capabilities might co... 

【文章来源】：山西医科大学山西省

【文章页数】：59 页

【学位级别】：硕士

【文章目录】：
Abbreviations
Abstract
Introduction
    1 Effects of sex hormones on the immune response
    2 Sex hormones and macrophage functions
    3 Steroid and apoptosis
    4 Interactions between L.D and macrophage
    5 Questions
Materials and methods
Results
    1 BMMs deprived of M-CSF die through an apoptotic way
    2 Effect of testosterone on apoptosis of BMMs
    3 Effect of cyproterone on Te-induced apoptosis of BMMs
    4 Effects of sex hormones on L.D infection of Ana-Ⅰ
Discussions
Conclusions
References
Acknowledgements



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