生物制品 的翻译结果
本文关键词:应用PCR技术检测兽医生物制品中污染病毒的研究,由笔耕文化传播整理发布。
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生物制品
TSN group: 1 mL/(kg·d) TSN-ⅡA (China Pharmacy Biological Products Examination Institute, batch number: S02001300, 1 kg/bag) was injected into rats in TSN group at the beginning of the 8th week for 10 successive weeks, and all rats were killed in the 18th week.
丹参酮组:从饲养至第8周开始,丹参酮ⅡA(中国药品生物制品检定所,批号S02001300,1kg/包)以1mL/(kg·d)剂量腹腔注射,持续用药10周,第18周处死;
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The rINFα1contents of 2 lots of samples (manufactured by Shanghal Institute of Biological Products) detected by the method were 19. 5 and 21.9μg/dose, respectively.
应用此方法测定上海生物制品研究所生产的rHuIFNα1(20μg/支)两批含量分别为19.5μg/支及21.9μg/支。
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Results:The purity of the resultant product was higher than 98.2%,the total yield approximately 65%,and contaminated endotoxin below than 2 EU·(106IU)-1·ml-1.Conclusion:An effective and suitable protocol has been established for the preparation of rh-TNFαD3a,and three batches of rh-TNFαD3a have been passed the inspection of National Institute for the Control of Pharmaceutical and Biological Products.
结果:纯度>98.2%,回收率约为65%,内毒素<2Eu·(106IU)-1·ml-1。 结论:建立了适宜的rh-TNFαD3a纯化方法,连续三批原料和制剂通过国家卫生部药品生物制品检定所检定,符合WHO有关基因工程产品临床用药标准,为过渡到临床验证打下了基础。
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At present, the cell strain used in Changchun Institute of Biological Products was constructed in the late 1980's, the yield of which is 1-2 mg HBsAg/48 hr/L and the products demanded exceed supplied.
长春生物制品所目前生产所用细胞株构建于二十世纪八十年代末,产量在1~2 mg HBsAg/48 hr/L,产品供不应求。
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Resveratrol group: Rats were injected with 5, 15 and 45 resveratrol mg/kg provided by Hunan Huaguang Biological Products Company Limited (batch number: 20050221, purity ≥99%) and ligated after 10 minutes.
白藜芦醇组:按5,15,45mg/kg剂量静脉注射白藜芦醇(购自湖南华光生物制品有限公司,生产批号:20050221,纯度≥99%)10min后结扎。
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②Hippocampus neuronal morphology and cell activity: After seven-day culture, the differentiated cells were divided randomly into 3 groups: Rg1 pretreatment group: After pretreated with Rg1 (1, 2, 4, 8 and 16 μmol/L, provided by China Materia Medica Biological Product Inspection Institute, batch code: 0703-200221) for 24 hours, the cells were incubated in 40 μmol/L Aβ25-35, totally for 24 hours.
②海马神经元形态及细胞活力观察:细胞培养7d至分化成熟状态,然后被随机分为3组:人参皂苷Rg1预处理组(分为1,2,4,8,16μmol/L5个浓度组),首先每加入各浓度的Rg1(中国药品生物制品检定所提供,批号:0703-200221)预作用24h后,再加入40μmol/L淀粉样β蛋白25~35共孵育24h;
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The feed groups including basic feed(group A,control),supplemented with 1.0%(group B),2.5%(group C) and 5.0%(group D) of compound biological product were used to make feed experiments,and the fish bodies were randomly selected from each group to determine their growth indexes and biochemical compositions of fish bodies.
在基础饲料中分别添加不同质量分数的复合生物制品,包括不添加(A组)、1.0%(B组)、2.5%(C组)、5.0%(D组)进行饲喂试验,分别从每组随机抽取鱼体,测定其生长指标和鱼体生化组成。
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Studies on the Application of PCR Technique to Testing for Virus Pollution Causing by Veterinary Biological Product
应用PCR技术检测兽医生物制品中污染病毒的研究
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The material of national standard endotoxin(NSE) used in our country was produced by Shanghai institute of biological product in 1997, although it satisfied the request as standard material on biological activity and its biological character was analysis partly in the beginning.
目前我国使用的细菌内毒素国家标准品(批号981)的原料是由上海生物制品研究所于1997年制备的,虽然在生物学活性上满足了作为标准物质的要求,但在制备之初仅对其生物学活性进行了分析,没有理化性质分析数据,无法与国际标准品和其它国家的标准品相比对,并且使用近八年,库存量日渐减少,也需要尽快制备新一批的国家标准品。
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A clinical investigation of the level of lipids, glucose and uric acid influenced by a fish biological product
鳀鱼生物制品对人体血脂血糖血尿酸影响的临床研究
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Applacation of GMP and TQC in the Biologicals Production Management
良好生产管理规范与全面质量管理及其在生物制品生产管理中的应用
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Mouse shall be provided by Experimental Animal Center of Changchun Biologicals Institute.
由生物制品所实验动物中心提供。
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4. Yolk treated with 9.2kGy was completely up to the standard of veterinarian biologicals after sterility test, mycoplasmas test, exogenous virus test, COFAL test, safety test and potency test.
4.9.2kGy辐照后的高免卵黄液经无菌检验、支原体检验、外源性病毒检验、禽白血病病毒检验、安全性检验和效力检验证实完全符合兽医生物制品的要求。
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RESULTS:Ocurrence rate and mortality of allergic shock induced by antimicrobials,Chinese materia medica and biologicals occupied the front3places in sequence,and drugs for intravenous administration resulted in the highest rate(61.30%).
结果 :抗微生物药物、中草药、生物制品的过敏性休克发生率及死亡率居前3位 ; 静脉用药发生率最高 ,占61 30% ;
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The method has the po- tential for detection of residual DNA in other biologicals prepared with continuous cell lines.
本法同样适用于传代细胞制备的其它生物制品中细胞残余DNA的检测。
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Strategies and Measures of Biosafety Control to Genetically Modified Veterinary Biologics II Biosafety assessment
兽用基因工程生物制品的安全控制对策与措施( II )——生物安全性评价
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Strategies and Measures of Biosafety Control to Genetically Modified Veterinary Biologics III. Biosafety control measures
兽用基因工程生物制品的安全控制对策与措施(III)——生物安全控制措施
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Conclusion All the quality indexes of SARS virus NS-1 strain complied with the Technical Point in Pre-clinical Study of Inactivated SARS Vaccine and the Chinese Requirements for Biologics 2000.It may be used as the seeds for production of inactivated SARS vaccine.
结论SARS病毒NS1株各项指标均符合《SARS病毒灭活疫苗临床前研究技术要点》和《中国生物制品规程》2000年版要求,可作为SARS灭活疫苗生产用毒种。
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Results A total of 79 cell lines from the cell bank for production of biologics were tested from 2003 to March 2006,of which 10 lines(12.7%) were contaminated with mycoplasma and 5 lines(6.3%) with adventitious viruses.
结果自2003~2006年3月间共检测了用于生物制品生产用细胞库细胞79株。 结果显示,被检测的79株细胞中,支原体污染细胞10株,污染阳性率为12.7%;
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Strategies and Measures of Biosafety Control to Genetically Modified Veterinary Biologics I. Biosafety control by laws, regulations and directives and biosafety regulation
兽用基因工程生物制品的安全控制对策与措施(I)——法律法规体系的建立和安全管理
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biological products
High-performance size exclusion chromatography of biological products
High-performance size exclusion chromatography has been applied to the analysis and separation of a range of 'biological products' - substances and preparations used in human medicine that cannot be completely defined by chemical and physical means.
Freeze-Drying/ Lyophilization of Pharmaceutical and Biological Products, Louis Rey and Joan C.
The calculation algorithms developed allow one to determine the aerodynamic and temperature-moisture characteristics with account for natural convection and arbitrary shape of storehouses in order to optimize the storing of biological products.
The materials were thus deemed suitable for detailed characterization of elemental concentration to lead to recommended values and to bring these biological products to reference material status.
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biological product
FDA regulation of allogeneic islets as a biological product
The major production costs (50-90%) for typical biological product resides in the purification strategy.
Simulation of the heat-and-mass transfer in the mound of stored biological product with centers of spontaneous heating
The mathematical model of the interdependent heat-and-mass transfer in a mound of stored biological product in view of the centers of spontaneous heating is offered.
The biological product enhanced oil degradation relative to the control, but to a lesser extent than the nutrient additions alone.
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biologicals
In therapierefrakt?ren Situationen kommen neuerdings Biologicals erfolgversprechend zum Einsatz.
Air-lift bioreactors containing suspended or immobilized animal cells have been used for the production of a variety of high-value biologicals.
Neuere Kasuistiken beschreiben den lokalen Einsatz von Calcineurinantagonisten und Imiquimod und den systemischen Einsatz von Biologicals zur erfolgreichen Therapie des Granuloma anulare.
In this role, the development of the interferons has provided a model for other biologicals which are currently entering phase I clinical trials.
The objective of this study was to assess the long-term safety and tolerability of biologicals in a clinical setting.
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biologics
Recent debates have centered on where biologics should be positioned within the current treatment strategy so as to maximize efficacy while balancing risk.
This review highlights the current position biologics hold relative to conventional therapies within the current "step-up" treatment strategy.
Dehydroepiandrosterone and biologics in the treatment of systemic lupus erythematosus
Use of biologics in the treatment of childhood rheumatic diseases
The current systemic anti-tumor necrosis factor (TNF)-α therapies with biologics ameliorate disease in 60% to 70% of RA patients.
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本文关键词:应用PCR技术检测兽医生物制品中污染病毒的研究,由笔耕文化传播整理发布。
,本文编号:241887
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