自拟治喘汤治疗儿童哮喘发作期临床观察

发布时间：2018-01-11 10:21

本文关键词：自拟治喘汤治疗儿童哮喘发作期临床观察　出处：《辽宁中医药大学》2013年硕士论文　论文类型：学位论文

【摘要】：目的: 观察郭振武老师自拟中药汤剂治疗小儿哮喘发作期（热哮）的临床疗效、中医症候体征、外周血EOS的测定以及血清总IgE的改善，并与西药氨茶碱片进行对照，客观的评价治疗组的临床疗效。方法：通过随机的试验设计，收集符合研究要求的100例患儿，并将此100例患儿随机分为治疗组50例和对照组50例。治疗组接受郭振武老师治疗哮喘的经验方，并随症加减。对照组接受氨茶碱片，7天为一个疗程，观察四周。观察治疗前后治疗组与对照组患儿的临床综合疗效改善情况，，中医症候及体征的改善情况，治疗前后外周血嗜酸性粒细胞（EOS）及血清总IgE水平的改变。数据运用SPSS17.0统计软件进行分析观察结果。结果： 1.治疗组应用郭振武老师治疗小儿哮喘的经验方治疗小儿哮喘发作期的总有效率为88%，对照组总有效率为52%，两组比较具有统计学意义（P＜0.05㖞。 2.治疗组与对照组在中医证候体征方面比较，有显著差异（P＜0.05㖞。 3.治疗后两组外周血EOS均有所下降，与治疗前自身相比，有显著差异（P＜0.05㖞，治疗后两组间无显著差异(p＞0.05). 4.治疗后两组血清总IgE水平均较治疗前下降，与治疗前自身相比，有显著差异（P＜0.05㖞，治疗后两组间无显著差异(p＞0.05).结论：郭振武老师治疗小儿哮喘经验方治疗小儿哮喘发作期患儿，能明显改善哮喘患儿的临床症状，降低外周血嗜酸性粒细胞（EOS）以及血清总IgE水平，具有良好的疗效，值得在临床上进一步推广。
[Abstract]:Objective: To observe the clinical effect of Guo Zhenwu's self-made traditional Chinese medicine decoction on children's asthma attack (heat asthma), the signs of TCM symptoms, the determination of EOS in peripheral blood and the improvement of serum total IgE. And compared with western medicine aminophylline tablets, objective evaluation of the clinical efficacy of the treatment group. Methods: A randomized trial was conducted to collect 100 children who met the requirements of the study. The 100 children were randomly divided into treatment group (n = 50) and control group (n = 50). The treatment group was treated with Guo Zhenwu's experience prescription in treating asthma, and the control group received aminophylline tablets for 7 days as a course of treatment. Observe four weeks. Observe the treatment group and control group before and after treatment of children with comprehensive clinical efficacy improvement, TCM symptoms and signs of improvement. The changes of eosinophil eosinophils (Eos) and serum total IgE levels before and after treatment were observed by SPSS17.0 software. Results: 1. The total effective rate of the treatment group with Guo Zhenwu's experience prescription in treating children's asthma was 88%, while the control group's total effective rate was 52%. There was significant difference between the two groups (P < 0.05). . 2.Compared with the control group in TCM syndromes, there was significant difference between the treatment group and the control group (P < 0.05). . 3.After treatment, the EOS in peripheral blood of both groups decreased, and there was significant difference between the two groups before treatment (P < 0.05). There was no significant difference between the two groups after treatment (P > 0.05). 4. After treatment, the serum total IgE levels in both groups were lower than those before treatment, and there was significant difference between the two groups before treatment (P < 0.05). There was no significant difference between the two groups after treatment, P > 0.05. Conclusion: teacher Guo Zhenwu's experience prescription in treating children with asthma can obviously improve the clinical symptoms of children with asthma. The decrease of eosinophil eosinophils in peripheral blood and the level of serum total IgE have good curative effect and deserve to be popularized in clinic.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R272

【参考文献】