麻杏甘石汤治疗小儿肺炎随机对照临床研究文献的Meta分析

发布时间：2018-01-26 12:40

本文关键词： 麻杏甘石汤小儿肺炎咳嗽哮喘 Meta分析　出处：《中华中医药杂志》2017年11期 　论文类型：期刊论文

【摘要】：目的:分析评价麻杏甘石汤治疗小儿肺炎的疗效。方法:通过计算机检索1949年-2014年CNKI、VIP、CBM三大数据库关于麻杏甘石汤治疗小儿肺炎的文献539篇,选择符合要求的随机对照试验、临床对照试验,采用协作网Cochrane,Rev Man 5.2统计软件进行Meta分析。结果:共纳入39篇随机对照临床研究的文献,计4959例患者,经Meta分析结果显示,临床疗效组间比较有显著性差异。其中,麻杏甘石汤vs西医治疗:OR=4.13,95%CI[2.54,6.70],Z=5.73,P0.00001;RR=1.20,95%CI[1.13,1.28],Z=5.57,P0.00001;RD(total)=0.16,95%CI[0.11,0.21],Z=6.02,P0.00001。麻杏甘石汤+西医常规治疗vs西医常规治疗:OR=5.11,95%CI[3.37,7.76],Z=7.68,P0.00001;RR=1.19,95%CI[1.14,1.24],Z=7.81,P0.00001;RD=0.15,95%CI[0.11,0.18],Z=8.41,P0.00001。麻杏甘石汤+抗生素v s抗生素:O R=5.22,95%CI[4.04,6.74],Z=12.68,P0.00001;RR=1.22,95%CI[1.18,1.26],Z=13.01,P0.00001;RD=0.17,95%CI[0.15,0.19],Z=14.29,P0.00001。结论:麻杏甘石汤治疗小儿肺炎优于单纯西医疗法及抗生素治疗。
[Abstract]:Objective: to analyze and evaluate the curative effect of Ma Xing Ganshi decoction in treating pediatric pneumonia. Methods: from 1949 to 2014, CNKI VIP was searched by computer. There were 539 articles on the treatment of infantile pneumonia with Maxingganshi decoction in three databases of CBM. Random controlled trial and clinical controlled trial were selected and Cochrane was used. Rev Man 5.2 statistical software was used for Meta analysis. Results: a total of 4959 patients were included in 39 articles of randomized controlled clinical study. The results of Meta analysis showed that the results of Meta analysis were as follows. There were significant differences in the clinical efficacy between the two groups. Among them, Ma Xing Ganshi decoction vs Western Medicine treatment: ORX 4.1395 CI. [2.54 / 6.70 / C 5.73 / P 0.00001 RRN 1.2095 CI. [1 / 13 / 1.28 / P = 5.57 / P 0.00001 / RDtotal / 0.1695 / CI. [Maxingganshi decoction: routine western medicine treatment vs conventional western medicine treatment: 5. 1195 CI. [3.37 + 7.76] Zang 7.68 P0.00001 RRN 1.1995 CI. [1.14 / 1.24 / c 7.81 / P 0.00001 / RD/ 0.1595 / CI. [Maxingganshi decoction antibiotic v / s antibiotic V / s antibiotic O / R = 5.22 / 95 / CI = 0.11 + 0.18] ZZH 8.41g / p 0.00001.An antibiotic V / s antibiotic V / s = O / R = 5.22 / 95 / CI. [4.04 / 6.74 / c / r = 1.2295 / cis / r = 1.2295 / r = 1.2295 / r = 1.2295 / r = 1.2295 / r = 1.2295. [1.18v 1.26] Zang 13.01g P0.00001RD 0.1795 CI. [Conclusion: maxing Ganshi decoction is superior to western medicine therapy and antibiotic therapy in the treatment of pediatric pneumonia.
【作者单位】：北京中医药大学;
【基金】：北京中医药大学新奥奖励基金项目(No.2015-XAJLJJ-002)~~
【分类号】：R272
【正文快照】： 小儿肺炎是儿科最常见的多发病之一,主要病因为病毒和细菌感染,多见于5岁以下儿童,临床表现为发热、咳嗽、气促、呼吸困难和肺部湿Up音。本病属于中医学的咳嗽、哮证、喘证、痰饮、肺胀、肺痈等范畴。本文收集麻杏甘石汤治疗小儿肺炎的随机对照临床研究文献进行Meta分析,为中

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