止泻食疗方治疗小儿湿热型泄泻的临床研究

发布时间：2018-02-08 15:39

本文关键词： 止泻食疗方小儿泄泻湿热泻临床研究　出处：《新疆医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:观察止泻食疗方治疗小儿湿热型泄泻的临床疗效,同时评估止泻食疗方的安全性。为了临床上能更好的治疗小儿湿热泻提供指导和参考建议,更好的发挥我国传统中医学的优势。方法:将符合小儿湿热泻诊断标准、纳入标准、排除标准的170例患者随机分入观察组(食疗方组)85例和对照组(西药组)85例,均3次/日,疗程为5天,观察并记录治疗前后患儿的主要、次要症状、血便常规的情况,应用SPSS17.0软件对数据进行统计学分析,客观的分析两组患儿的治疗总有效率,如实记录实验研究过程中出现的任何不良事件。结果:(1)两组患儿治疗前一般情况如性别、年龄、病程、临床症状总积分等基数资料经统计学分析差异均无统计学意义,具有可比性(P0.05)。(2)两组治疗后组间比较:食疗方组治疗后临床症状总积分比西药组下降较为明显,差异有显著的统计学意义(P0.01),说明食疗方组在改善湿热泻临床症状方面较对照组有优势。(3)组内自身治疗前后比较:两组患儿经治后临床症状总积分均有降低,差异有显著统计学意义(P0.01),说明两种治疗方法都可以改善湿热型泄泻患儿的临床症状。(4)两组治疗后临床疗效及证候疗效比较差异具有统计学意义(P0.05),说明止泻食疗方治疗小儿湿热泻有一定优势。(5)两组治疗后血、便常规异常情况改善比较,差异无统计学意义(P0.05),说明治疗组在改善血、便常规异常情况方面与对照组相比没有优势。(6)两组患儿在治疗期间未出现不良事件,安全性好。结论:止泻食疗方治疗小儿湿热型泄泻具有较好的临床效果,尤其是改善患儿临床症状方面具有优势,而且安全、方便,具有临床应用和推广价值。
[Abstract]:Objective: to observe the clinical effect of Zhixie decoction in the treatment of diarrhea in children with damp-heat type, and to evaluate the safety of Zhixie decoction in order to provide guidance and advice for the better treatment of damp-heat diarrhea in children. Methods: 170 patients who met the diagnostic criteria of damp and heat diarrhea in children were randomly divided into the observation group (85 cases in the treatment group) and the control group (85 cases in the western medicine group, 3 times a day), and the control group (85 cases in the western medicine group) were randomly divided into the observation group (85 cases) and the control group (85 cases). The course of treatment was 5 days. The main and secondary symptoms and routine blood stool were observed and recorded before and after treatment. The data were statistically analyzed by SPSS17.0 software, and the total effective rate of the two groups was analyzed objectively. Results there was no significant difference between the two groups in the basic data such as sex, age, course of disease, total score of clinical symptoms and so on before treatment. Comparison between the two groups after treatment: the total score of clinical symptoms in the treatment group was significantly lower than that in the western medicine group. The difference was statistically significant (P 0.01), indicating that the treatment group had an advantage over the control group in improving the clinical symptoms of dampness and heat diarrhea. The comparison between the two groups before and after self-treatment showed that the total score of clinical symptoms of the two groups was decreased after treatment. The difference was statistically significant (P 0.01), indicating that both treatment methods can improve the clinical symptoms of children with damp-heat diarrhea.) the difference of clinical and syndromic effects between the two groups after treatment is statistically significant (P 0.05), which indicates that Zhixie decoction can improve the clinical symptoms of children with diarrhea of dampness and heat type. Treatment of children with damp-heat diarrhea has a certain advantage. Compared with the control group, there was no significant difference between the two groups in the improvement of routine abnormal condition (P 0.05), which indicated that the treatment group had no advantage over the control group in improving the blood and stool routine abnormality.) there were no adverse events in the two groups during the treatment period. Conclusion: Zhixie decoction has good clinical effect in treating children with diarrhea of damp-heat type, especially in improving the clinical symptoms of children. It is safe and convenient, and has clinical application and popularization value.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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