胎粪吸入综合征的诊治进展

发布时间：2018-02-20 06:38

本文关键词： 胎粪吸入综合征肺动脉高压炎症肺损伤诊断治疗　出处：《蚌埠医学院》2013年硕士论文　论文类型：学位论文

【摘要】：胎粪吸入综合征（meconium aspiration syndrome，MAS）是指胎儿在子宫内或分娩过程中缺氧，出现宫内喘息或初始呼吸，导致胎粪吸入，生后出现以呼吸窘迫为主要表现，同时伴有其他脏器受损的一组综合征。有高度可变的发病率和死亡率。MAS的病因及发病机制是多因素的，目前仍不十分清楚。现主要通过临床表现、实验室检查和X线检查、超声多普勒检查等诊断MAS及判断病情轻重程度。重症MAS可以是致命性的，常常并发呼吸衰竭，肺气漏，，持续肺动脉高压。目前研究表明，在常规治疗的基础上联合应用一氧化氮吸入、肺表面活性物质、高频振荡通气、体外膜肺等可以大大降低病死率，提高生存质量及减少并发症的发生。本文主要对MAS的诊治进展作一综述。
[Abstract]:Meconium aspiration syndrome (meconium aspiration syndrome) is defined as anoxia in the womb or delivery, intrauterine wheezing or initial breathing, which results in meconium aspiration and respiratory distress after birth. At the same time, a group of syndromes with damage to other organs. The etiology and pathogenesis of highly variable morbidity and mortality. MAS is multivariate, but it is still not very clear. Now it is mainly through clinical manifestation, laboratory examination and X-ray examination. Severe MAS can be fatal, often accompanied by respiratory failure, pulmonary gas leakage, persistent pulmonary hypertension. Combined use of nitric oxide inhalation, pulmonary surfactant, high frequency oscillatory ventilation, extracorporeal membrane lung, etc., on the basis of routine treatment, can greatly reduce the mortality. To improve the quality of life and reduce the incidence of complications, this article reviews the progress of diagnosis and treatment of MAS.
【学位授予单位】：蚌埠医学院
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R722.1

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