癫痫儿童的行为问题及临床相关影响因素的研究

发布时间：2018-02-21 23:41

本文关键词： 癫痫儿童行为问题临床因素　出处：《大连医科大学》2012年硕士论文　论文类型：学位论文

【摘要】：目的：评估癫痫儿童的行为问题；分析不同临床状况下癫痫儿童的行为表现；探讨影响癫痫儿童行为问题的临床相关因素。方法：收集癫痫儿童的一般资料和临床资料(包括发作类型、发作频率、起病年龄、病程及用药数量)，同时采用父母用Achenbach儿童行为量表(CBCL)对84例癫痫儿童和61例正常儿童进行行为评定。通过卡方检验、t检验比较两组儿童一般情况、CBCL总分及各因子得分、异常行为问题发生率及不同性别癫痫儿童的行为表现。采用F检验比较病例组儿童不同发作类型、不同发作频率和不同用药数量的CBCL总分及各因子得分。采用单因素相关分析对癫痫儿童的临床特征与CBCL总分及各因子得分进行相关分析。运用多重线性回归分析筛选影响癫痫儿童行为问题的临床相关因素。结果：①癫痫儿童异常行为问题发生率为35.71%，与对照组比较差异有明显统计学意义（P0.01）。②两组儿童CBCL比较结果：病例组在社会退缩、躯体主诉、焦虑/抑郁、社交问题、思维问题、注意问题、违纪问题、攻击行为、内向性、外向性行为问题得分及行为问题总分均高于对照组，差异有统计学意义（均P0.05）。③病例组男性违纪问题得分高于女性，差异有统计学意义（P0.05）。④不同临床特征的病例组儿童CBCL比较结果：不同发作类型的三组注意问题、违纪行为、CBCL总分总体比较，差异有统计学意义(P0.05)；不同发作频率的三组注意问题总体比较差异有统计学意义(P0.05)；不同用药数量的三组躯体主诉、焦虑/抑郁、社交问题、CBCL总分总体比较，差异有统计学意义(P0.05)。⑤病例组CBCL与临床特征的相关分析结果：发作频率与注意问题、外向性问题正相关；起病年龄与焦虑/抑郁、社交问题、外向性问题、CBCL总分负相关；病程与躯体主诉、违纪问题、攻击行为、内向性问题、外向性问题、CBCL总分正相关。⑥多重线性回归分析结果：病程和起病年龄是癫痫儿童行为问题的主要临床影响因素，病程与CBCL总分正相关，，起病年龄与CBCL总分负相关。结论：①癫痫儿童存在广泛和明显的行为问题，其中除男性在违纪问题高于女性外，其它方面均未见明显的性别间差异。②癫痫的发作类型、发作频率、病程、起病年龄、用药数量等临床特征与行为问题存在不同程度的相关性。③病程和起病年龄是癫痫儿童行为问题的主要临床影响因素。
[Abstract]:Objective: to evaluate the behavioral problems of epileptic children, to analyze the behavior of epileptic children under different clinical conditions, and to explore the related clinical factors affecting the behavioral problems of epileptic children. Methods: the general and clinical data of epileptic children were collected, including the type of seizure, frequency of seizure, onset age, At the same time, 84 epileptic children and 61 normal children were assessed by parental Achenbach children behavior scale. The general situation of the two groups was compared by chi-square test and the total score of CBCL and the scores of each factor were compared by chi-square test. The incidence of abnormal behavior problems and the behavior of epileptic children of different genders. F test was used to compare the different seizure types of children in the case group. Single factor correlation analysis was used to analyze the clinical characteristics of epileptic children and the total score of CBCL and the scores of each factor. Multiple linear regression analysis was used to analyze the relationship between the clinical characteristics of epileptic children and the total score of CBCL and the scores of each factor. To screen the clinical related factors affecting behavioral problems in epileptic children. Results the incidence of abnormal behavior problems in children with epilepsy was 35.71%. There was significant difference in CBCL between the two groups. The results were as follows: social withdrawal, body complaints, anxiety / depression, social problems, thinking problems in the case group. The scores of attention problem, discipline violation problem, aggression behavior, introversion, extroversion behavior problem and the total score of behavior problem were higher than those of the control group, and the difference was statistically significant (P0.05.3). The difference was statistically significant (P 0.05). 4. The results of comparison of CBCL in children with different clinical characteristics were as follows: attention problem of three groups with different seizure types, total score of CBCL of violation of discipline, The difference was statistically significant (P 0.05); there were significant differences among the three groups with different seizure frequency (P 0.05); the total scores of body complaints, anxiety / depression, and social problems in the three groups with different dosage of drugs were compared as a whole. There was significant difference in the correlation between CBCL and clinical characteristics in patients with P0.055.The results showed that the frequency of onset was positively correlated with attention problems and extroverted problems, and the onset age was negatively correlated with anxiety / depression, social problems and extroverted problems. The course of disease was positively correlated with the total score of CBCL. The results showed that the course of disease and onset age were the main clinical influencing factors of behavioral problems in epileptic children. The course of disease was positively correlated with the total score of CBCL, and the onset age was negatively correlated with the total score of CBCL. Conclusion there are extensive and obvious behavioral problems in children with epilepsy at 1: 1. Except for the problem of violation of discipline in males and females, there is no significant gender difference in seizure type, frequency, course and age of onset of epilepsy. The clinical characteristics such as quantity of drugs and behavioral problems were related to different degrees. 3 the course of disease and age of onset were the main clinical influencing factors of behavioral problems in epileptic children.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R742.1

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