桑杏哮咳颗粒治疗小儿CVA发作期燥邪犯肺型的临床研究

发布时间：2018-02-22 06:01

本文关键词： 桑杏哮咳颗粒 CVA 燥邪犯肺型临床研究　出处：《云南中医学院》2017年硕士论文　论文类型：学位论文

【摘要】：目的:本课题通过观察桑杏哮咳颗粒治疗小儿咳嗽变异性哮喘(CVA)发作期燥邪犯肺型的临床疗效,对该方治疗小儿CVA的有效性进行客观、真实的评估,以期为该方药的临床应用提供一定依据,为小儿CVA的治疗提供新的思路与方法。方法:本研究纳入符合标准的患儿72例,用数字随机分组法分为治疗组桑杏哮咳颗粒组和对照组布地奈德气雾剂组,研究过程中剔除12例,最终每组患儿有效病例各30例。分别对治疗前后两组患儿的主、次要症状积分及总症状积分进行组内、组间比较,综合的评价桑杏哮咳颗粒的临床疗效。结果:1.总有效率治疗组为90.00%,对照组为76.67%,经比较,P0.05,有统计学差异,表明治疗组总疗效优于对照组;2.治疗前后两组对改善咳嗽频率、咳嗽性质、咳嗽程度、咳痰、鼻干、唇干、咽干、饮食差、大便干方面比较,PO.05,有统计学差异,表明两组对CVA的治疗都是有效的;3.治疗后两组在改善咽干、饮食差、大便干方面,P0.01,有显著性统计学差异,表明治疗组在改善这三方面效果明显优于对照组;4.治疗后两组对咳痰的改善,PO.05,无统计学差异,表明两组治疗对咳痰的改善效果相当;5.对照组治疗后咽干、饮食差积分和治疗前比较,积分无下降,反而有所增加,PO.05,有统计学差异,表明对照组对咽干、饮食差情况改善不明显;6.治疗过程中60例患儿无明显不良反应。结论:通过对桑杏哮咳颗粒治疗小儿CVA发作期燥邪犯肺型的临床观察,进而对桑杏哮咳颗粒治疗小儿燥邪犯肺型CVA发作期的临床疗效给予肯定,值得在临床上应用、推广。
[Abstract]:Objective: to observe the clinical effect of Sangxingxingke granule on infantile cough variant asthma (CVA) during the attack period, and to evaluate the effectiveness of the prescription in treating children with CVA objectively and realistically. In order to provide a certain basis for the clinical application of the prescription, and to provide a new way of thinking and method for the treatment of CVA in children. Methods: 72 cases of children who met the criteria were included in this study. The treatment group and control group were randomly divided into two groups: the treatment group and the control group. 12 cases were excluded from the study, and 30 effective cases were found in each group. The two groups were divided into two groups before and after the treatment, respectively, before and after treatment, and 30 cases were treated with budesonide aerosol. The secondary symptom score and total symptom score were compared within the group, and comprehensive evaluation of the clinical efficacy of Sangxingxingke granule. Results: 1. The total effective rate was 90.00g in the treatment group and 76.67g in the control group. There was statistical difference between the two groups (P 0.05). The results showed that the total curative effect of the treatment group was better than that of the control group 2.There was statistical difference between the two groups in improving cough frequency, cough nature, degree of cough, expectoration, trunk of nose, dry lip, dry pharynx, poor diet and dry stool. The results showed that the treatment of CVA in both groups was effective. After treatment, there was a significant difference between the two groups in improving the pharyngeal dryness, poor diet and dry stool (P 0.01). The results showed that the improvement of expectoration in the treatment group was obviously better than that in the control group 4.After treatment, there was no statistical difference between the two groups in the improvement of expectoration, which indicated that the improvement effect of the two groups on expectoration was equivalent to that in the control group. The pharynx dry after treatment in the control group was better than that in the control group. Compared with before treatment, the score of dietetic difference was not decreased, but increased by PO.05. the difference was statistically significant, indicating that the control group had a positive effect on pharyngeal dryness. There were no obvious adverse reactions in 60 children during the course of treatment. Conclusion: the clinical observation of Sangxingxingke granule in treating the lung type of dryness evil in children with CVA attack. The clinical effect of Sangxingxingke granule on infantile dryness and evil invading lung type CVA is confirmed, which is worth applying and popularizing in clinic.
【学位授予单位】：云南中医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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