学生缺铁性贫血常用筛查方法比对分析

发布时间：2018-02-24 00:31

  本文关键词： 贫血 缺铁性 回归分析 学生保健服务　出处：《中国学校卫生》2017年12期 　论文类型：期刊论文

【摘要】：目的比对干化学法、血球仪与氰化高铁法等常用学生缺铁性贫血检测方法的准确性和重复性,为学生缺铁性贫血的准确诊断提供参考。方法使用全血样品,分别采用几种检测方法对参加健康体检的121份成人空腹静脉血样本进行测定,分析不同方法与金标准氰化高铁法在判定贫血上的异同。结果血球仪和干化学(A)2种方法与氰化高铁法配对结果,差值分别为(0.29±2.77)(-0.15±2.80)g/L,差异无统计学意义(P0.05);而干化学法(B)与干化学法(C)2种方法与氰化高铁法检测结果相比,差值分别平均低(4.97±5.37)(6.85±4.51)g/L(t值分别为10.19,16.71,P值均0.01)。4种检测方法血红蛋白检测值与氰化高铁法检测结果的相关系数均在0.98以上(P0.01),连续检测20份样本的标准差或变异系数均低于行业标准规定值。结论干化学法(A)的准确性和重复性基本可以和血球仪及氰化高铁法一致,而干化学法(B)和干化学法(C)的准确性与氰化高铁法存在一定差异。在现场缺铁性贫血筛查中,可采用方便快捷的干化学法替代氰化高铁法,但需要严格的质量控制。
[Abstract]:Objective to compare the accuracy and repeatability of the methods of iron deficiency anemia in students, such as dry chemistry method, blood cell analyzer and high iron cyanide method, so as to provide a reference for the accurate diagnosis of iron deficiency anemia in students. The fasting venous blood samples of 121 adults who took part in the physical examination were measured by several methods. The differences and similarities between the different methods and the gold standard high iron cyanide method in the determination of anemia were analyzed. The difference values were 0.29 卤2.77 ~ 0.15 卤2.80 g / L, respectively. There was no significant difference (P 0.05), but the results of dry chemical method (B) and dry chemical method were compared with those of high iron cyanide method. The average difference value was 4.97 卤5.37g / L = 6.85 卤4.51g / L ~ (t) = 10.19 ~ 16.71g / L ~ (-1) P, respectively. The correlation coefficients of hemoglobin detection value and cyanoferrate test result were all above 0.98 (P < 0.01). The standard deviation or coefficient of variation of 20 consecutive samples were all lower than that of row. Conclusion the accuracy and reproducibility of dry chemical method are basically the same as that of blood cell analyzer and high iron cyanide method. The accuracy of dry chemical method (B) and dry chemical method (C) is different from that of high iron cyanide method. In the field screening of iron deficiency anemia, the convenient and quick dry chemical method can be used to replace the high iron cyanide method, but strict quality control is needed.
【作者单位】： 北京航空航天大学实验学校;北京市疾病预防控制中心;
【分类号】：R725.5
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本文编号：1528207