185例新生儿血清钙、磷、碱性磷酸酶与维生素D状况研究

发布时间：2018-03-03 16:21

本文选题：新生儿　切入点：钙　出处：《重庆医学》2017年03期 　论文类型：期刊论文

【摘要】：目的探讨不同胎龄、出生体质量、出生季节的新生儿血清钙、磷、碱性磷酸酶(ALP)与维生素D状况。方法选取2015年1月至2015年12月期间在该院住院的185例新生儿作为研究对象,根据新生儿的胎龄分为27~32周组、32~37周组及37~41周组;根据出生体质量分为极低出生体质量新生儿组(VLBW组,1 500g)、低出生体质量新生儿组(LBW组,1 500~2 500g)、正常出生体质量新生儿组(NBW组,2 500~3 999g);根据出生季节分为冬春组(公历12月至5月)和夏秋组(公历6月至11月)。比较各组之间的血清钙、磷、ALP与25-羟基维生素D(25OHD)水平。结果 27~32周组的血钙显著低于另外两组,血磷显著高于另外两组,ALP、25OHD缺乏率显著高于37~41周组,25OHD显著低于37~41周组,差异均有统计学意义(P0.05)。32~37周组的血钙、25OHD显著低于37~41周组,差异均有统计学意义(P0.05)。全部新生儿中VLBW组、LBW组、NBW组分别占17.3%、44.9%、37.8%。VLBW组的血钙显著低于另外两组,25OHD显著低于NBW组,差异均有统计学意义(P0.05)。LBW组的血钙显著低于NBW组,差异有统计学意义(P0.05)。冬春组的25OHD显著低于夏秋组,25OHD缺乏率显著高于夏秋组,差异均有统计学意义(P0.05)。结论不足32周的早产儿出生时血磷与ALP水平较高,25OHD缺乏较严重,故需要对小胎龄早产儿进行血钙、磷、ALP、维生素D状况的监测。
[Abstract]:Objective to investigate the serum calcium, phosphorus, alkaline phosphatase (ALPP) and vitamin D status of newborns at different gestational ages, birth body weight, and birth season. Methods 185 newborns hospitalized in our hospital from January 2015 to December 2015 were selected as the study subjects. According to the gestational age of the newborns, they were divided into two groups: the group of 27 ~ 32 weeks and the group of 37 ~ 41 weeks. According to birth weight, it is divided into very low birth weight newborn group (VLBW), low birth weight newborn group (LBW) and normal birth weight newborn group (n = 2 500 ~ 3 999g / g), and is divided into winter and spring group (Gregorian 12) according to birth season. The serum calcium levels were compared between the summer and autumn groups (June to November of Gregorian calendar). Results the levels of serum calcium in 2732 weeks group were significantly lower than those in the other two groups, and the blood phosphorus deficiency rate was significantly higher than that in the other two groups. The blood calcium 25 OHD in the VLBW group was significantly lower than that in the other two groups, and the difference was statistically significant (P 0.05). The blood calcium in the VLBW group was significantly lower than that in the NBW group (P < 0. 05). The blood calcium in the VLBW group was significantly lower than that in the other two groups (P < 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P < 0. 05). The difference was statistically significant (P 0.05). The blood calcium deficiency rate in winter and spring group was significantly lower than that in summer and autumn group, which was significantly higher than that in summer and autumn group. Conclusion the blood phosphorus and ALP levels of premature infants with less than 32 weeks were lower than that of preterm infants at birth, so it was necessary to monitor the blood calcium, phosphorus and vitamin D status of premature infants at small gestational age.
【作者单位】：南方医科大学第三附属医院儿科;
【分类号】：R722.1

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