3~5岁儿童潮气呼吸法检测呼出气一氧化氮方法对比分析

发布时间：2018-03-06 03:25

本文选题：呼出气一氧化氮　切入点：学龄前期　出处：《中国实用儿科杂志》2017年03期 　论文类型：期刊论文

【摘要】：目的对比3~5岁儿童清醒状态下,使用面罩潮气呼吸法和口腔潮气呼吸法所测出的呼出气一氧化氮(Fe NO),探讨3~5岁儿童Fe NO的检测方法。方法将广州市妇女儿童医疗中心2016年1月至2016年8月符合入选标准的55例儿童作为研究对象,分别使用面罩潮气呼吸法和口腔潮气呼吸法进行Fe NO检测,并对结果进行对比分析。结果无咳喘症状儿童无论有无鼻炎,使用口腔潮气呼吸法测出的Fe NO均明显低于面罩潮气呼吸法所测结果:分别使用口腔潮气呼吸法和面罩潮气呼吸法测Fe NO,有鼻炎患儿为(7.8±10.6)×10~(-9)和(15.8±9.9)×10~(-9);无鼻炎患儿为(5.0±4.5)×10~(-9)和(14.0±10.0)×10~(-9),均P0.05;有咳喘症状儿童,无论有无鼻炎,使用口腔潮气呼吸法测出Fe NO明显低于面罩潮气呼吸法所测结果;分别使用口腔潮气呼吸法和面罩潮气呼吸法测Fe NO,有鼻炎患儿为6.1×10~(-9)[(2.1~16.3)×10~(-9)]和11.6×10~(-9)[(4.1~26.5)×10~(-9)],无鼻炎患儿为4.6×10~(-9)[(1.9~9.9)×10~(-9)]和11.5×10~(-9)[(6.5~25.8)×10~(-9)],均P0.05。结论 3~5岁儿童使用潮气呼吸法进行Fe NO检测时,口腔潮气呼吸法比面罩潮气呼吸法更能正确反应气道炎症真实情况。~
[Abstract]:Objective to compare the awake state of children aged 3 to 5 years old, Using mask tidal breathing method and oral tidal breathing method to detect the exhalation nitric oxide (no) and nitric oxide (FNO) in children aged 3 to 5 years, the method of detecting Fe no in children aged 3 ~ 5 years was studied. Methods the Guangzhou Medical Center for Women and Children from January 2016 to August 2016 was enrolled in the study. A total of 55 children were selected as subjects. Fe no was detected by mask tidal breathing method and oral tidal breathing method, and the results were compared and analyzed. Results No cough and asthma symptoms were found in children with or without rhinitis. Fe no measured by oral tidal breathing method was significantly lower than that measured by mask tidal breathing method: in children with rhinitis, it was 7.8 卤10.6 脳 10 ~ (-9) 脳 10 ~ (9) and 15.8 卤9.9) 脳 10 ~ (10) ~ (-9), and that in children without rhinitis was 5.0 卤4.5 脳 10 ~ (10 ~ (-9)) and 10 ~ (10 ~ (-9)) in children without rhinitis, respectively, and in children without rhinitis it was 5.0 卤4.5 脳 10 ~ (-9)), and that in children without rhinitis was 5.0 卤4.5 脳 10 ~ (-9)). 14. 0 卤10. 0) 脳 10 ~ (-9) (P < 0. 05). With or without rhinitis, the measurement of FeNO by oral tidal breathing method was significantly lower than that by mask tidal breathing method. The determination of Fe _ (no) in children with rhinitis by oral tidal breathing method and mask tidal breathing method was 6.1 脳 10 ~ (-9) [2.1g ~ (16.3) 脳 10 ~ (-9)) and 11.6 脳 10 ~ (-9) ~ (9)) respectively. Conclusion when children without rhinitis use tidal breathing method, they are 4.6 脳 10 ~ (-9)) [1.99 ~ (9) 脳 10 ~ (-9)) and 10 脳 10 ~ (-9) ~ 9) [6.525.8) 脳 10 ~ (-9)). Oral tidal breathing is a more accurate response to airway inflammation than mask tidal breathing.
【作者单位】：广州医科大学附属广州市妇女儿童医疗中心;
【基金】：国家卫计委卫生行业科研专项(201502025)
【分类号】：R725.6

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