活血益肾法治疗儿童左肾静脉压迫综合征的临床观察

发布时间：2018-03-09 00:40

本文选题：儿童　切入点：左肾静脉压迫综合征　出处：《福建中医药大学》2015年硕士论文　论文类型：学位论文

【摘要】：目的：通过观察活血益肾法治疗儿童左肾静脉压迫综合征的临床疗效,总结导师临床经验,提高临床疗效。方法：收集2010年至2014年期间我院左肾静脉压迫综合征患儿30例,采用随机数字表法分为中药治疗组(简称A组)和空白对照组(简称B组)各15例。两组的性别、年龄、病程分布均具有可比性(P=0.4660.05,P=0.7150.05, P=0.7100.05)。A组采用自拟的活血益肾方(药物组成：桃仁5g、红花5g、当归5g、赤芍9g、白茅根15g、生地黄15g、山药12g、山茱萸9g、茯苓9g、牡丹皮15g等)治疗,水煎,日1剂,2次/日,6个月为1个疗程；B组不采取任何治疗措施,观察6个月。观察两组初诊时和初诊后6个月的左肾静脉内径值、尿红细胞计数,并观察中药治疗组治疗前后的临床症状体征。结果：(1)初诊时,A组与B组比较：仰卧位和脊柱后伸位时的LRV内径比值均无显著差异(P=0.0900.05,P=0.7140.05),具有可比性；初诊后6个月,A组仰卧位和脊柱后伸位时的LRV内径比值明显小于B组,差异非常显著(P=-0.0120.05,P=0.0070.01)；中药治疗组治疗6个月后,仰卧位和脊柱后伸位时的LRV内径比值明显小于治疗前,差异非常显著(P=0.0000.01,P=0.0000.01)。(2)初诊时,A组的尿红细胞计数与B组比较无显著差异(P=-0.5020.05),具有可比性；初诊后6个月,A组的尿红细胞计数明显少于B组,差异非常显著(P=0.0000.01)；中药治疗组治疗6个月后的尿红细胞计数明显少于治疗前,差异非常显著(P=0.0000.01)。(3)中药治疗组的临床疗效：治愈5例,显效8例,无效2例,总有效率86.6%。结论：活血益肾法治疗儿童左肾静脉压迫综合征,可以降低LRV内径比值、减少尿红细胞的排泄,从而改善临床症状和体征,提高临床有效率。活血益肾法通过改善肾脏血液循环,降低LRV内径比值,达到降低LRV压力,改善临床症状的目的。
[Abstract]:Objective: to observe the clinical effect of activating blood circulation and tonifying the kidney in treating left renal vein compression syndrome in children, summarize the clinical experience of tutor and improve the clinical effect. Methods: from 2010 to 2014, 30 cases of left renal vein compression syndrome were collected in our hospital. A randomized digital table method was used to divide Chinese medicine treatment group (group A for short) and blank control group (group B for short) with 15 cases each. The course of disease in group A was treated with self-made prescription for activating blood circulation and tonifying kidney (drug composition: peach seed 5g, safflower 5g, Angelica sinensis 5g, Radix Paeoniae rubra 9g, Radix Alba 15g, raw yellow 15g, yam 12g, Cornus officinalis 9g, Poria cocos 9g, peony skin 15g). The left renal vein diameter and urine red blood cell count were observed at first visit and 6 months after treatment in group B without any treatment. The clinical symptoms and signs before and after treatment in traditional Chinese medicine treatment group were observed. Results compared with group B at first visit, there was no significant difference in the ratio of LRV inner diameter in supine position and spinal extension position. The ratio of LRV diameter in supine position and spinal extension position in group A was significantly lower than that in group B at 6 months after initial diagnosis, and the difference was very significant (P < 0.01). After 6 months of treatment, the ratio of LRV diameter in supine position and spinal extension position in Chinese medicine treatment group was significantly lower than that in group B, and the ratio of LRV diameter in supine position and spinal extension position was significantly lower than that in group B after 6 months of treatment. There was no significant difference in urine erythrocyte count between group A and group B at the beginning of diagnosis, and the urine erythrocyte count in group A was significantly lower than that in group B at 6 months after the first visit, and the urine erythrocyte count in group A was significantly lower than that in group B at 6 months after initial diagnosis, and there was no significant difference between group A and group B in urine erythrocyte count. The number of urine red blood cells in the treatment group was significantly lower than that before treatment, and the difference was very significant (P < 0.05). The clinical efficacy of the Chinese medicine treatment group was as follows: 5 cases cured, 8 cases markedly effective, and 2 cases ineffective. Conclusion: the treatment of left renal vein compression syndrome in children by activating blood circulation and tonifying the kidney can reduce the ratio of LRV inner diameter, reduce the excretion of urine red blood cells and improve the clinical symptoms and signs. The method of activating blood circulation and tonifying the kidney can reduce the pressure of LRV and improve the clinical symptoms by improving the circulation of kidney and reducing the ratio of LRV inner diameter.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R272

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