新生儿外科感染性疾病病原菌分布与耐药性

发布时间：2018-03-16 09:24

本文选题：儿外科　切入点：医院感染　出处：《中国消毒学杂志》2017年08期 　论文类型：期刊论文

【摘要】：目的了解新生儿外科感染性疾病的病原菌分布与耐药情况,为合理用药提供依据。方法采用回顾性调查方法,对湖北省某医院509例住院新生儿外科感染性疾病患儿送检病原学标本进行检测和分析。结果从509例患儿送检标本中检出致病菌阳性402例,阳性率78.98%;感染病种以肛周脓肿和脐炎居多,占68.4%。检出致病菌居前3位的分别为金黄色葡萄球菌、大肠埃希菌和肺炎克雷伯菌。金黄色葡萄球菌对青霉素G和氨苄西林耐药率为100%;对阿莫西林/克拉维酸、头孢西丁、克林霉素、苯唑西林和红霉素耐药率均接近40%。大肠埃希菌和肺炎克雷伯菌对氨苄西林耐药率最高,对其他种类抗菌药物均不同程度耐药。结论该医院新生儿外科感染性疾病的致病菌以金黄色葡萄球菌、大肠埃希菌和肺炎克雷伯菌为主,应依据药敏试验结果合理使用抗菌药物。
[Abstract]:Objective to investigate the distribution and drug resistance of pathogenic bacteria in neonatal surgical infectious diseases and to provide evidence for rational use of drugs. The pathogenic specimens of 509 hospitalized neonates with surgical infectious diseases in a hospital in Hubei Province were detected and analyzed. Results 402 cases of pathogenic bacteria were detected from 509 samples. The positive rate was 78.98. The most common infectious diseases were perianal abscess and umbilical inflammation, accounting for 68.4%. Staphylococcus aureus was the first three pathogens to be detected. Escherichia coli and Klebsiella pneumoniae. Resistance of Staphylococcus aureus to penicillin G and ampicillin was 100; amoxicillin / clavulanic acid, cefoxitin, clindamycin, The resistance rates of oxacillin and erythromycin were close to 40. Escherichia coli and Klebsiella pneumoniae had the highest resistance to ampicillin. Conclusion Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae are the main pathogens of neonatal surgical infectious diseases in this hospital. Antimicrobial agents should be used reasonably according to the results of drug sensitivity test.
【作者单位】：湖北省中医院湖北省中医药研究院;武汉市妇女儿童医疗保健中心;
【分类号】：R722.13

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