手足口病患儿临床特征及重症危险因素Logistic回归分析

发布时间：2018-03-17 12:55

本文选题：手足口病　切入点：临床特征　出处：《中外医学研究》2016年05期 　论文类型：期刊论文

【摘要】：目的:探讨分析手足口病患儿的临床特征及重症病例的危险因素。方法:选择2014年1月-2015年2月笔者所在医院诊断为手足口病的患儿150例,分为普通手足口组(普通组,n=100)和重症手足口组(重症组,n=50),比较两组患儿性别、年龄、居住地及临床表现和实验室检查,通过多因素分析手足口病的临床特征及筛选出重症手足口病的危险因素。结果:手足口重症组和普通组的年龄、居住地、体温、热程、是否发生院内感染、神经症状发生率比较,差异均有统计学意义(P0.05)。Logistic回归分析提示肌跃性抽动、肢体震颤、昏迷、巴宾斯基征阳性、踝阵挛、白细胞、血糖、CRP、ESR可能是手足口病重症感染的危险因素。结论:出现高热、肌跃性抽动、精神差、呕吐等神经症状且伴有白细胞、血糖、CRP、ESR等升高时,应该高度怀疑进展为重症手足口病的可能。
[Abstract]:Objective: to investigate the clinical characteristics and risk factors of hand, foot and mouth disease (HFMD) in children with hand, foot and mouth disease (HFMD). Methods: 150 cases of HFMD were selected from January 2014 to February 2015 in our hospital. The children were divided into two groups: common hand and foot mouth group (normal group) and severe hand foot mouth group (severe group). Sex, age, residence, clinical manifestation and laboratory examination were compared between the two groups. The clinical characteristics of HFMD and the risk factors of HFMD were analyzed by multivariate analysis. Results: age, residence, body temperature, fever, nosocomial infection were found in severe hand-foot-mouth disease group and common group. Compared with the incidence of neurologic symptoms, the difference was statistically significant (P 0.05). Logistic regression analysis showed that muscle jump twitch, limb tremor, coma, Babinsky sign positive, ankle clonus, white blood cell, and so on. Conclusion: high fever, muscular twitching, poor spirit, vomiting and other neurological symptoms may be the risk factors for severe infection of HFMD. The possibility of progression to severe HFMD should be highly suspected.
【作者单位】：邵阳市中心医院;
【分类号】：R725.1

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