孤独症患儿血清催产素水平与社交能力关系的研究

发布时间：2018-03-18 01:24

  本文选题：孤独性障碍　切入点：催产素　出处：《重庆医学》2017年14期 　论文类型：期刊论文

【摘要】：目的探讨孤独症儿童与健康儿童血清催产素水平差异及其与孤独症儿童社交能力的关系。方法选取3~5岁孤独症患儿25例与健康儿童20例分别接受血清催产素水平测量,采用社交反应量表评定孤独症儿童社交能力。结果独立样本t检验显示孤独症患儿血清催产素水平低于健康儿童,比较差异有统计学意义(P0.05)。孤独症儿童患者血清催产素水平与其社交能力呈负相关(r=-0.735,P0.01)。多元线性回归模型分析显示孤独症儿童患者中,催产素水平是影响社交能力的因素(F=11.931,P0.01)。结论与健康儿童相比,孤独症儿童患者存在血清催产素水平异常,血清催产素水平可能是影响其社交能力的因素。
[Abstract]:Objective to explore the difference of serum oxytocin level between autistic and healthy children and its relationship with social ability of autistic children. Methods Serum oxytocin levels were measured in 25 autistic children aged 3 ~ 5 years and 20 healthy children. Results the independent sample t test showed that the serum oxytocin level of autistic children was lower than that of healthy children. The serum oxytocin level in autistic children was negatively correlated with their social ability. The multivariate linear regression analysis showed that the serum oxytocin level in autistic children was negatively correlated with their social ability. Conclusion compared with healthy children, the serum oxytocin level in autistic children is abnormal, and the serum oxytocin level may be the factor that affects the social ability of autistic children.
【作者单位】： 重庆市第九人民医院儿童孤独症康复治疗中心;重庆市第九人民医院药学研究室;重庆市第九人民医院药剂科;
【基金】：重庆市医学科研项目(20143047)
【分类号】：R749.94
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