中西医结合序贯疗法治疗小儿支原体肺炎痰热闭肺证的临床研究

发布时间：2018-03-23 10:01

本文选题：中西医结合序贯疗法　切入点：小儿肺炎支原体肺炎　出处：《山东中医药大学》2017年硕士论文

【摘要】：目的:采用中西医结合序贯疗法和阿奇霉素序贯疗法治疗感染肺炎支原体所致小儿肺炎中痰热闭肺证型,观察症状改善情况,客观评价疗效、有效性和安全性,以便更好地发挥中医药在治疗肺炎喘嗽中的积极作用。方法:收集2016年8月~2016年12月于烟台市中医医院院住院治疗的小儿肺炎支原体肺炎病例,选取30例痰热闭肺证病例,按1:1比例随机分为2组(对照组、治疗组):两组各15例,对照组采用阿奇霉素进行治疗并对症处理;治疗组在阿奇霉素常规治疗的基础上进行辨证论治服用五虎汤合贝母瓜蒌散加减;治疗并随访至出院21天,自治疗初始每日观察患儿症状、体征,并建立、填写观察表,记录相应实验室检查结果,对中西医结合序贯疗法治疗小儿支原体肺炎的临床疗效进行分析。结果:治疗组疾病痊愈1例,显效14例,有效0例,无效0例,愈显率100%;对照组疾病痊愈0例,显效13例,有效2例,无效0例,愈显率86.67%。中医证候疗效治疗组治愈1例,显效9例,有效5例,无效0例,愈显率66.67%;对照组治愈0例,显效5例,有效10例,无效0例,愈显率33.33%。两组比较虽然P0.05,但显示治疗组疗效可靠,且对于中医症候改善优于对照组,显示中西医结合序贯治疗方案疗效可靠。结论:中西医结合序贯疗法治疗小儿肺炎支原体肺炎能明显、快速改善临床症状,无明显不良反应,安全有效。
[Abstract]:Objective: to treat the syndrome of phlegm heat blocking lung in children with pneumonia caused by mycoplasma pneumoniae, observe the improvement of symptoms, evaluate the curative effect, effectiveness and safety objectively by the combination of traditional Chinese and western medicine and azithromycin. Methods: from August 2016 to December 2016, the cases of mycoplasma pneumoniae pneumonia in children hospitalized in Yantai traditional Chinese Medicine Hospital were collected, and 30 cases of phlegm heat blocking lung syndrome were selected. At 1:1, they were randomly divided into two groups (control group, treatment group: 15 cases each, control group treated with azithromycin and symptomatic treatment; On the basis of routine treatment of azithromycin, the treatment group was treated with Wuhu decoction and beimu Gualou Powder on the basis of differentiation of symptoms and signs, followed up until 21 days after discharge, observed the symptoms and signs of the children, established and filled out the observation form, from the beginning of treatment to 21 days after treatment. The results of laboratory examination were recorded and the clinical efficacy of sequential therapy of integrated traditional Chinese and western medicine in the treatment of mycoplasma pneumonia in children was analyzed. Results: in the treatment group, 1 case was cured, 14 cases were markedly effective, 0 case was effective, and 0 case was ineffective. In the control group, 0 cases were cured, 13 cases were effective, 2 cases were effective, 0 cases were ineffective, and 86.67.The curative effect of TCM syndrome treatment group was 1 case, 9 cases effective, 5 cases effective, 0 cases ineffective, and 66.67% obvious recovery rate, while in control group, 0 cases were cured, 1 case was cured, 9 cases were effective, 5 cases were effective, 0 cases were ineffective, and 66.67% were cured in the control group. There were 5 cases of remarkable effect, 10 cases of effective and 0 cases of ineffective. The effective rate was 33.333.Although the two groups were compared with each other (P0.05), the curative effect of the treatment group was reliable, and the improvement of TCM symptoms was better than that of the control group. Conclusion: Sequential treatment of mycoplasma pneumoniae pneumonia in children with combined traditional Chinese and western medicine can improve clinical symptoms quickly without obvious adverse reactions and is safe and effective.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R725.6

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