人参四逆汤加味治疗不同类型实体瘤患儿化疗不良反应的临床效果分析

发布时间：2018-03-30 05:18

本文选题：不同类型实体瘤　切入点：儿童　出处：《辽宁中医杂志》2017年04期

【摘要】：目的:探讨人参四逆汤加味治疗不同类型实体瘤患儿化疗不良反应的临床效果分析。方法:将2015年1月—2016年6月在本院儿科治疗的80例不同类型实体瘤患儿随机分为两组,均采用化疗治疗的方法,出现化疗不良反应,对照组采用西医常规治疗的方法,在此基础上观察组采用人参四逆汤加味治疗,6个月后比较两组患儿疲乏、恶心呕吐、纳差、白细胞低下等不良反应的改善情况、外周血象各指标、化疗依从性以及生活质量。结果:观察组治疗后疲乏、恶心呕吐、纳差、体重减轻、脱发等不良反应明显较对照组减轻,差异有统计学意义(P0.05);观察组治疗后白细胞计数、血小板计数、血红蛋白浓度明显高于对照组,差异有统计学意义(P0.05);观察组化疗依从性及化疗完成率均高于对照组,差异有统计学意义(P0.05);观察组治疗后生活质量改善情况明显优于对照组,差异有统计学意义(P0.05)。结论:人参四逆汤加味治疗不同类型实体瘤患儿化疗不良反应的临床效果显著,有效减轻化疗对机体的损伤,增强耐受性,提高生活质量,具有积极的临床意义。
[Abstract]:Objective: to investigate the clinical effect of modified Ginseng Sini decoction in treating children with different types of solid tumors. Methods: 80 children with different types of solid tumors who were treated in pediatrics from January 2015 to June 2016 were randomly divided into two groups. All the patients were treated with chemotherapy, and the patients in the control group were treated with routine western medicine. On the basis of this, the observation group was treated with Ginseng Sini decoction. Six months later, the fatigue, nausea, vomiting and anorexia were compared between the two groups. The improvement of adverse reactions such as leukopenia, peripheral blood index, chemotherapeutic compliance and quality of life. Results: the adverse reactions such as fatigue, nausea and vomiting, anorexia, weight loss and alopecia in the observation group were significantly less than those in the control group. After treatment, the white blood cell count, platelet count and hemoglobin concentration in the observation group were significantly higher than those in the control group, and the difference was statistically significant (P 0.05), the chemotherapeutic compliance and the completion rate of chemotherapy in the observation group were higher than those in the control group. The quality of life in the observation group was significantly better than that in the control group, and the difference was statistically significant (P 0.05). Conclusion: the adverse effects of chemotherapy in children with different types of solid tumors treated with modified Ginseng Sini decoction are significant. It has positive clinical significance to reduce the damage of chemotherapy, enhance tolerance and improve the quality of life.
【作者单位】：南方医科大学南方医院;
【基金】：广东省中医药局中医药强省建设专项资金广东省名中医师承项目(2100601)
【分类号】：R730.5

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