防哮饮联合吸入用布地奈德治疗肺气虚证儿童哮喘缓解期的临床观察

发布时间：2018-03-30 06:46

本文选题：防哮饮　切入点：布地奈德　出处：《中药材》2017年06期

【摘要】：目的:研究防哮饮联合吸入布地奈德对肺气虚证缓解期儿童哮喘的临床疗效,并探讨其对儿童肺功能和气道反应性的影响。方法:选取2015年6月~2016年6月在浙江省新华医院儿科就诊的112例肺气虚证缓解期哮喘患儿随机分为观察组和对照组,对照组患儿给予雾化吸入布地奈德治疗,观察组患儿雾化吸入布地奈德并口服防哮饮,疗程为3个月,比较治疗前后两组患儿的中医证候积分,并进行综合临床疗效评价,检测两组患儿的肺功能及呼吸道反应性。结果:(1)治疗后观察组患儿鼻痒喷嚏、流涕、咳嗽、气短、出汗、面色、语音、乏力、畏风等中医证候积分较对照组患儿显著降低(P0.01);(2)观察组患儿总有效率显著高于对照组(P0.05);(3)治疗后观察组患儿肺功能指标VT/kg、Ti/Te、TPTEF/TE、VPEF/VE、TEF25%、TEF50%及TEF75%均较对照组显著升高(P0.01),Rr和PEF较对照组显著降低(P0.01);(4)治疗后观察组患儿呼吸道反应性参数D_(min)、C_(min)、SGrs和SGrs/Grs均较对照组显著升高(P0.01)。结论:防哮饮联合吸入布地奈德治疗肺气虚证缓解期哮喘患儿具有较好的临床疗效,可显著改善患儿的肺功能并降低其呼吸道反应性。
[Abstract]:Objective: to study the clinical effect of Fangxiao decoction combined with inhaled budesonide on asthmatic children with lung qi deficiency syndrome in remission period. Methods: from June 2015 to June 2016, 112 children with asthma in remission of lung qi deficiency syndrome were randomly divided into observation group and control group. Children in the control group were treated with budesonide, and those in the observation group were treated with budesonide and oral budesonide for 3 months. The scores of TCM syndromes of the two groups were compared before and after treatment, and the comprehensive clinical efficacy was evaluated. Results after the treatment, the children in the observation group had itching, sneezing, runny, coughing, shortness of breath, sweating, complexion, speech, fatigue, etc. The total effective rate of the observation group was significantly higher than that of the control group (P 0.05)) after treatment, the pulmonary function index of the observation group was significantly higher than that of the control group. The pulmonary function indexes of the observation group were significantly higher than that of the control group. The pulmonary function indexes of the observation group were 50% and 75% higher than those of the control group. After treatment, the respiratory reactivity parameters of the observation group were significantly higher than that of the control group. Conclusion: the combination of P0.01and inhaled budesonide has a better clinical effect in the treatment of asthmatic children with asthenia of lung qi syndrome. It can significantly improve the pulmonary function and reduce the respiratory tract reactivity in children.
【作者单位】：浙江省新华医院呼吸科;浙江省中医院儿科;
【基金】：浙江省中医药优秀青年人才基金计划项目(2012ZQ013)
【分类号】：R725.6

【相似文献】