新生儿感染性休克发生与疾病危重评分和多脏器功能损害的关系研究

发布时间：2018-04-02 14:08

本文选题：新生儿疾病危重病例评分　切入点：多脏器功能损害　出处：《中华医院感染学杂志》2017年02期

【摘要】：目的探讨新生儿感染性休克发生与疾病危重评分和多脏器功能损害的关系,为临床早期诊断及早预防提供理论依据。方法回顾性分析2010年1月-2015年12月在医院治疗的45例感染性休克患者的临床资料;45例患儿轻度休克(轻度组)10例,中度休克(中度组)28例,重度休克(重度组)7例;比较不同休克程度患儿新生儿疾病危重病例评分、脏器功能损害等情况。结果轻度组与中度组感染性肺炎的发生率较高,显著高于重度组,重度组以败血症的发病率最高,显著高于轻度组与中度组,差异有统计学意义(P0.05);重度组新生儿疾病危重评分85.7%患儿70分,显著高于轻度组和中度组,轻度组50.0%患儿评分90分,显著高于中度组及重度组,差异有统计学意义(P0.05);轻度组100.0%的患儿1个脏器功能衰竭,中度组53.6%的患儿1个脏器功能衰竭,重度组14.3%的患儿1个脏器功能衰竭,轻度组显著高于中度组及重度组,中度组高于重度组,差异有统计学意义(P0.05);轻度组无3个及4个脏器衰竭的病例,重度组57.1%的患儿2个脏器衰竭,显著高于轻度组,差异有统计学意义(P0.05)。结论新生儿感染休克程度重的患儿,新生儿疾病危重病例评分越低,脏器功能损害个数越多。
[Abstract]:Objective to explore the relationship between neonatal septic shock and disease severity score and multiple organ function damage, and to provide theoretical basis for early diagnosis and prevention of neonatal septic shock.Methods the clinical data of 45 patients with septic shock who were treated in hospital from January 2010 to December 2015 were retrospectively analyzed. There were 45 cases of mild shock (10 cases of mild shock, 28 cases of moderate shock (moderate group) and 7 cases of severe shock group (severe shock group).To compare the score of neonatal disease critical cases and organ function damage in children with different degrees of shock.Results the incidence of infectious pneumonia in mild group and moderate group was higher than that in severe group. The incidence of septicemia in severe group was the highest and significantly higher than that in mild group and moderate group.There was a significant difference between the two groups (P < 0.05), the neonatal disease critical score of severe group (85.7%) was significantly higher than that of mild group and moderate group (90 points), and the score of mild group (50.0%) was significantly higher than that of moderate group and severe group (90 points).The difference was statistically significant (P < 0.05), one organ failure was found in 100.0% of children in mild group, one organ failure in 53.6% of children in moderate group, and one organ failure in 14.3% of children in severe group, which was significantly higher in mild group than that in moderate group and severe group.There were significant differences between moderate group and severe group (P 0.05), but there were no 3 or 4 organ failure cases in mild group, and 57.1% in severe group, which were significantly higher than that in mild group (P 0.05).Conclusion the lower the score of severe neonatal shock, the more organ damage.
【作者单位】：郑州大学附属医院南阳市中心医院儿科;
【基金】：河南省教育厅科学技术研究重点项目(132114712125)
【分类号】：R720.597

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