新生儿监护病房无乳链球菌临床分布及耐药性分析

发布时间：2018-04-05 19:14

本文选题：新生儿　切入点：无乳链球菌　出处：《中国感染控制杂志》2017年09期

【摘要】：目的了解医院新生儿监护病房无乳链球菌临床分布及采取耐药性,为抗菌药物的使用及采取干预措施提供参考依据。方法收集2010—2014年某院新生儿监护病房新生儿送检的标本,对新生儿分离的62株无乳链球菌来源科室和药敏试验结果进行分析。结果 62株无乳链球菌的科室分布以足月新生儿监护病房为主,占64.52%;标本来源以血为主,占90.33%,其次为脑脊液(6.45%)、痰和分泌物(均为1.61%)。无乳链球菌对四环素的耐药率最高,为79.03%;对红霉素和克林霉素的耐药率均为74.19%,对左氧氟沙星的耐药率为40.32%,对青霉素、氨苄西林100%敏感。结论无乳链球菌感染在新生儿监护病房中以足月新生儿监护病房为主,对多种抗菌药物有较高的耐药率,青霉素和氨苄西林可作为治疗无乳链球菌感染的优选药物。
[Abstract]:Objective to investigate the hospital neonatal intensive care unit of Streptococcus agalactiae take clinical distribution and resistance, and to provide reference for the use of antimicrobial drugs and intervention measures. Methods from 2010 to 2014 in a hospital in NICU neonatal samples of newborn, 62 strains of Streptococcus agalactiae from departments and drug susceptibility test results were analyzed. Results 62 strains of Streptococcus agalactiae in neonatal ICU Department distribution, accounting for 64.52%; the blood samples, accounting for 90.33%, followed by cerebrospinal fluid (6.45%), sputum and secretion (1.61%). Streptococcus agalactiae resistant to tetracycline. The highest rate was 79.03%; the rate of resistance to erythromycin and clindamycin were 74.19%, resistant to levofloxacin was 40.32%, sensitive to penicillin, ampicillin was 100%. Conclusion in term neonates in neonatal intensive care unit in neonatal streptococcal infection The intensive care unit has a high rate of resistance to a variety of antimicrobial agents. Penicillin and ampicillin can be used as the best drug for the treatment of Streptococcus free Streptococcus.

【作者单位】：陆军总医院附属八一儿童医院出生缺陷防控关键技术国家工程实验室儿童器官功能衰竭北京市重点实验室;
【基金】：中国博士后科学基金项目(2013M542472)
【分类号】：R446.5;R722.1

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