急性呼吸道感染患儿肺炎支原体和肺炎衣原体病原学特征分析

发布时间：2018-04-08 19:14

本文选题：急性呼吸道感染　切入点：肺炎支原体　出处：《中国病原生物学杂志》2017年02期

【摘要】：目的了解对急性呼吸道感染住院患儿肺炎支原体和肺炎衣原体病原学特征,为临床诊疗提供指导。方法采集2013-2015年间在我院住院的急性呼吸道感染儿童患者的血清样本,采用ELISA法检测血清MP-IgM和血清CP-IgM,对肺炎支原体和肺炎衣原体感染特征进行分析。结果 1376例急性呼吸道感染住院患儿血清样本中共分离233株病原体,阳性率16.93%,其中肺炎支原体214株(91.85%),肺炎衣原体19株(8.15%)。2013年病原体阳性率12.26%(39/318),肺炎支原体和肺炎衣原体分别为30株和9株;2014年病原体阳性率16.05%(74/461),肺炎支原体和肺炎衣原体分别为68株和6株;2015年的病原体阳性率20.10%(120/597),肺炎支原体和肺炎衣原体分别为116株和4株。春季分离病原体58株,阳性率23.11%(58/251),均为肺炎支原体;夏季分离病原体86株,阳性率13.98%(86/508),均为肺炎支原体;秋季分离病原体38株,阳性率10.98%(38/346);冬季分离病原体51株,阳性率18.82%(51/271)。男性患儿分离病原体156株,阳性率18.44%(156/846);女性患儿分离病原体77株,阳性率14.53%(77/530)。1岁患儿病原体阳性率19.21%(44/229),1~3岁患儿病原体阳性率16.23%(93/573),3~6岁患儿病原体阳性率10.09%(35/347),6~12岁患儿病原体阳性率26.87%(61/227)。421例急性上呼吸道感染患者分离病原体124株,阳性率29.45%,543例急性支气管炎患者分离病原体92株,阳性率为16.94%,344例急性支气管肺炎患者分离病原体17株,阳性率为4.94%,均为肺炎支原体。52例喉气管支气管炎患者和16例哮喘合并感染患者均未检出病原体。结论肺炎支原体是急性呼吸道感染患儿的主要病原体,感染情况呈逐年升高趋势。男性6~12岁患儿,尤其是急性上呼吸道感染疾病检出率较高,临床治疗时应给予格外重视。
[Abstract]:Objective to investigate the etiological characteristics of mycoplasma pneumoniae and chlamydia pneumoniae in hospitalized children with acute respiratory infection and to provide guidance for clinical diagnosis and treatment.Methods Serum samples of children with acute respiratory infection (ARI) in our hospital from 2013 to 2015 were collected. Serum MP-IgM and CP-IgM were detected by ELISA method. The infection characteristics of mycoplasma pneumoniae and chlamydia pneumoniae were analyzed.Results A total of 1376 strains of pathogens were isolated from serum samples of 1376 hospitalized children with acute respiratory infection.In 2015, the positive rate of pathogens was 20.1010 / 597%, 116 strains of mycoplasma pneumoniae and 4 strains of chlamydia pneumoniae, respectively.There were 58 strains of pathogens isolated in spring, the positive rate was 23.1158 / 251, all were mycoplasma pneumoniae, 86 strains were isolated in summer, the positive rate was 13.98% 86 / 508%, all were mycoplasma pneumoniae; 38 strains of pathogens were isolated in autumn, the positive rate was 10.98% 346%; 51 strains were isolated in winter, the positive rate was 18.822%.156 strains of pathogens were isolated from male children, with a positive rate of 18.44%, while 77 strains of pathogens were isolated from female children.The positive rate was 29.45%, and the positive rate was 16.9444 cases of acute bronchopneumonia, 17 strains of pathogens were isolated from 543 patients with acute bronchitis, and 92 strains of pathogens were isolated from 543 cases of acute bronchitis.The positive rate of mycoplasma pneumoniae was 4.94. No pathogens were detected in 52 cases of laryngotracheal bronchitis and 16 cases of asthma complicated with infection.Conclusion Mycoplasma pneumoniae is the main pathogen in children with acute respiratory tract infection.The detection rate of acute upper respiratory tract infection is high in male children aged 6 to 12 years, so we should pay more attention to it in clinical treatment.
【作者单位】：兰州大学第一医院;
【分类号】：R725.6

【参考文献】