新生儿缺氧缺血性脑病的CT临床应用价值及随访观察

发布时间：2018-04-17 01:11

本文选题：新生儿 + 缺氧缺血性脑病　；参考：《山东大学》2012年硕士论文

【摘要】：目的通过对109例新生儿缺氧缺血性脑病(HIE)患儿进行CT检查、诊断及复查,探讨新生儿缺氧缺血性脑病的CT诊断价值及其分度与预后的关系。方法将109例(轻度61例、中度35例、重度组13例)有窒息缺氧病史,临床诊断为HIE的患儿行颅脑CT检查,初次CT扫描时间为生后5小时～15天,并按影像分级标准分轻、中、重三度,其中有76例在生后1-6个月内进行了CT复查。结果 ①109例HIE患儿脑CT平扫均有不同程度的脑水肿征象,CT值在8～18Hu之间。诊断为轻度HIE的66例；中度HIE的为31例,合并颅内出血9例；重度HIE的为12例,合并颅内出血7例。并将临床分度与CT分度资料经统计学处理进行比较分析,经统计学处理r=0.775,(P0.01),认为CT分级与临床分级之间有密切的相关性。②随访复查：最后一次CT复查所见,正常45例,单纯脑沟加深13例,硬膜下积液7例,脑软化7例,脑积水3例,脑萎缩3例,死亡2例。结论 CT扫描检查是诊断HIE的主要手段,能够准确的显示病变和范围,确定是否合并颅内出血及出血类型,为临床诊断和治疗提供客观的依据,对HIE预后有较好的评估价值。
[Abstract]:PurposeThrough CT examination, diagnosis and reexamination of 109 neonates with hypoxic-ischemic encephalopathy (HIEs), the value of CT diagnosis and the relationship between grading and prognosis of neonates with hypoxic-ischemic encephalopathy (HIE) were discussed.MethodOne hundred and nine children (61 mild, 35 moderate, 13 severe) had a history of asphyxia and anoxia. The children diagnosed as HIE were examined by craniocerebral CT. The first CT scan time was 5 hours and 15 days after living. According to the imaging grading standard, the children were divided into mild, moderate and severe degrees.Among them, 76 cases underwent CT reexamination within 1-6 months after birth.Result1109 children with HIE had different degrees of cerebral edema on plain CT scan and the CT value was between 8~18Hu.66 cases were diagnosed as mild HIE, 31 cases with moderate HIE, 9 cases with intracranial hemorrhage, 12 cases with severe HIE and 7 cases with intracranial hemorrhage.The data of clinical grading and CT grading were compared and analyzed by statistical analysis. The results showed that there was a close correlation between CT grading and clinical grade in 45 cases.There were 13 cases of sulcus deepening, 7 cases of subdural effusion, 7 cases of encephalomalacia, 3 cases of hydrocephalus, 3 cases of cerebral atrophy and 2 cases of death.ConclusionCt scan is the main method for the diagnosis of HIE, which can accurately show the lesion and range, determine whether the intracranial hemorrhage and the type of hemorrhage, provide an objective basis for clinical diagnosis and treatment, and have a good value in evaluating the prognosis of HIE.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R722.1

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