“王氏玉屏膏”贴敷治疗小儿反复呼吸道感染的回顾性研究

发布时间：2018-04-19 21:37

本文选题：王氏玉屏膏 + 贴敷　；参考：《南京中医药大学》2017年硕士论文

【摘要】：目的:观察"王氏玉屏膏"贴敷治疗小儿反复呼吸道感染(RRTI)的疗效,观察其对反复呼吸道感染患儿发作次数、急性发作时主要症状、发生呼吸道感染种类的影响,评价"王氏玉屏膏"贴敷治疗干预后疗效与疗程的关系,观察其贴敷疗法的不良反应,为该疗法的可行性提供临床依据。方法:选取符合反复呼吸道感染患儿100例,每年三伏天的初伏至末伏使用"王氏玉屏膏"进行贴敷治疗,一共10次,两次贴敷时间之间至少间隔2天,贴敷1-3年,观察每年次贴敷治疗后发生呼吸道感染的次数、病种、病程,每年次贴敷治疗后急性期主症积分对比以及次证改善情况对比,贴敷治疗后局部皮肤反应。结果:(1)"王氏玉屏膏"贴敷治疗小儿RRTI1、2、3年次的总有效率分别为80.77%、90.70%和 95.65%;显效率分别为 15.38%、32.56%和 60.87%,治疗效果与疗程呈正比。(2)贴敷治疗1、2、3年次发病次数降级百分比并无明显对比差异,而病程、病种降级例数百分比则呈逐年上升趋势,在病程降级方面,第2年次高于第1年,第3年远高于第2年,在病种降级方面第3年远高于第1年和2年。(3)贴敷1、2、3年次治疗前后感染期主症积分均明显减少。(4)"王氏玉屏膏"对食欲不振、神疲乏力、汗出量多、大便不调有改善作用。(5)在贴敷过程中,仅6例患儿出现轻度皮肤反应,无皮肤起泡破溃,体现了"王氏玉屏膏"贴敷治疗的安全性。结论:(1)贴敷1、2、3年对小儿RRTI治疗的有效率逐年递增,随着疗程增加,"王氏玉屏膏"贴敷疗法对小儿RRTI的治疗效果与疗程呈正比。(2)随着贴敷疗程增加,对RRTI患儿病种、病程降级的效果更加显著,贴敷疗程对病种降级、病程缩短效果在第3年尤为显著。(3)贴敷治疗后能够改善患儿食欲不振、神疲体倦、汗出量多、大便不调的症状。(4)该药临床用药安全可靠。
[Abstract]:Objective: to observe the efficacy of "Wang's Yuping plaster" in treating children with recurrent respiratory tract infection (RRTI), and to observe its effect on the frequency of recurrent respiratory tract infection, the main symptoms and the types of respiratory tract infection in children with recurrent respiratory tract infection. To evaluate the relationship between the curative effect and the course of treatment of "Wang's Yuping plaster" after intervention, to observe the adverse reaction of "Wang's Yuping plaster" and to provide clinical basis for the feasibility of the therapy. Methods: a total of 100 children with recurrent respiratory infection were treated with "Wang's Yuping plaster" for 10 times during the first and last three days of each year. The time interval between the two applications was at least 2 days and applied for 1-3 years. To observe the frequency of respiratory tract infection, disease type, course of disease, the comparison of main symptom score and the improvement of secondary syndrome after the treatment of sub-application every year, and the local skin reaction after application treatment. Results the total effective rate of "Wang's Yuping plaster" was 80.77% and 95.65%, respectively, and the effective rate was 15.385.56% and 60.87% respectively. The therapeutic effect was proportional to the course of treatment. There was no significant difference in the percentage of three years of incidence and demotion, and there was no significant difference in the percentage of the three years of incidence and demotion, and the total effective rate of "Wang's Yuping plaster" was 80.77% and 95.65%, respectively, and the effective rates were 15.385.56% and 60.87% respectively, and the therapeutic effect was proportional to the course of treatment. However, the percentage of downgrade cases of disease species increased year by year. The second year was higher than the first year, the third year was much higher than the second year, and the third year was much higher than the second year. In the demotion of disease species, the third year was much higher than that in the 1st and 2nd year. The main symptom score of infection period before and after 3 years treatment decreased significantly. 4) "Wang's Yuping ointment" had no appetite, was tired, and sweated more. In the course of application, only 6 cases had mild skin reaction and no skin blister burst, which reflected the safety of "Wang's Yuping Ointment" in the treatment of "Wang's Yuping Ointment". Conclusion the effective rate of RRTI treatment in children increased year by year in 3 years, and the effect of "Wang's Yuping Ointment" on the treatment of pediatric RRTI was proportional to the course of treatment. (2) with the increase of the course of application, the effective rate of treatment for children with RRTI increased with the increase of the course of treatment, and with the increase of the course of treatment, the types of diseases in children with RRTI were also increased. The effect of course of disease degradation was more significant, the course of treatment was significantly reduced by applying the course of treatment, and the effect of shortening the course of disease was especially significant in the third year.) after the application of the treatment, it could improve the children's loss of appetite, fatigue, sweating, and the amount of sweating. Symptoms of defecation disorder. 4) the drug is safe and reliable in clinical use.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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