某儿童医院耐甲氧西林金黄色葡萄球菌分布特征调查

发布时间：2018-04-22 22:14

本文选题：儿童 + 金黄色葡萄球菌　；参考：《中国感染控制杂志》2017年10期

【摘要】：目的调查某儿童医院耐甲氧西林金黄色葡萄球菌(MRSA)的分布特征,为预防和控制儿童MRSA感染提供依据。方法对2011—2015年入住该儿童医院的患儿进行回顾性分析,收集并分析患儿临床资料、分离病原菌、送检标本种类、医院感染情况等。结果 2011—2015年共检出金黄色葡萄球菌(SA)阳性患儿911例(1 108份阳性标本),其中MRSA阳性患儿494例(599份阳性标本),MRSA例数分离率为54.23%(分离率为54.06%);不同性别MRSA例数分离率比较,差异无统计学意义(P0.05);不同年龄组MRSA例数分离率比较,差异有统计学意义(P0.05)。血、穿刺液、分泌物、脓液MRSA分离率分别为68.97%、66.00%、55.81%、54.47%。SA检出率从2011年的0.61%上升至2015年的1.40%,MRSA分离率从2011年的21.74%上升至2015年的75.59%,差异均有统计学意义(均P0.05)。SA、MRSA医院感染发生率从2011年的0.198%,分别上升至2015年的2.697%、2.119%,均呈逐年上升趋势(均P0.05)。结论该儿童医院住院患儿MRSA分离率及医院感染发生率均呈逐年上升,急需加大监管力度,科学合理使用抗菌药物,及时消毒隔离,遏制MRSA在医院环境中的产生和传播。
[Abstract]:Objective to investigate the distribution of methicillin-resistant Staphylococcus aureus (MRSA) in a children's hospital and to provide evidence for prevention and control of MRSA infection in children. Methods retrospective analysis was carried out on the children admitted to the children's hospital from 2011 to 2015. The clinical data of the children were collected and analyzed. The pathogenic bacteria were isolated, the types of samples submitted to the hospital and the nosocomial infection were collected and analyzed. Results from 2011 to 2015, a total of 1 108 positive specimens were detected in 911 cases of Staphylococcus aureus positive, of which 494 cases were positive for MRSA and 599 cases were positive for MRSA. The isolation rate was 54.23% (the isolation rate was 54.06%). There was no significant difference (P 0.05), but there was significant difference in the separation rate of MRSA in different age groups (P 0.05). Blood, puncture fluid, secretions, The isolation rate of MRSA in pus was 68.97, 66.00 and 54.47.SA increased from 0.61% in 2011 to 1.40g% in 2015 to 75.599.The difference was statistically significant (all P0.05.SAMRSA increased from 0.198 in 2011 to 2015 in 2015). The value of 2.697% and 2.119% in 2000 showed an increasing trend year by year (all P 0.05). Conclusion the MRSA isolation rate and nosocomial infection rate of hospitalized children in this hospital are increasing year by year. It is urgent to strengthen supervision, use antibiotics scientifically and rationally, disinfect and isolate timely, and curb the generation and transmission of MRSA in hospital environment.
【作者单位】：安徽省儿童医院;
【基金】：安徽省2016年软科学研究专项(1607a0202055) 北京儿童医院集团2015年度科研课题(北儿集团学字[2015]33号(01))
【分类号】：R446.5;R725.1

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