寒热并用法治疗“寒热错杂型”儿童支气管哮喘急性发作期的临床研究

发布时间：2018-04-22 23:12

本文选题：解表清里、化痰平喘方 + 儿童支气管哮喘　；参考：《广州中医药大学》2012年硕士论文

【摘要】：目的：通过对研究对象治疗前后及组间相关疗效指标比较,综合评价解表清里、化痰平喘方治疗儿童哮喘急性发作期的疗效。初步探讨应用解表清里、化痰平喘方治疗急性发作期儿童支气管哮喘的疗效明确且显著,从而为其在临床上的推广运用奠定基础。方法：把符合研究标准的60例患儿,随机分组,按1：1分为治疗组及对照组。治疗组给予西药常规治疗+解表清里、化痰平喘方,每日一剂；对照组给予西药常规治疗。两组疗程均为5天。通过对治疗前和治疗后分别进行症状及体征积分观察,和肺功能的检测,运用SPASS17.0统计软件进行分析,观察两组的疗效差异,评价解表清里、化痰平喘方治疗儿童哮喘急性发作期的临床疗效。成果： 1.治疗5天后,治疗组与对照组均能有效改善患儿的总临床症状,治疗前后比较有显著性差异(P0.05),其中治疗组在改善总临床症状上,疗效优于对照组,具有统计学意义(P0.05)。 2.治疗组与对照组在中医总症状治疗前后积分变化的比较,有显著性差异(P0.05),其中治疗组总症状积分变化大于对照组,治疗组在改善症状方面优于对照组,具有统计学意义(P0.05)。 3.治疗组与对照组中医主症的临床控制的比较,及两组起效时间的比较,均有显著性差异(P0.05),其中治疗组在中医主症的临床控制、起效时间上,疗效优于对照组,具有统计学意义(P0.05)。 4.治疗5天后,治疗组与对照组均能有效改善肺功能(PEF、FEV1),治疗前后比较有显著性差异(P0.05),其中治疗组在改善肺功能方面优于对照组,具有统计学意义(P0.05)。结论：研究结果显示,应用解表清里、化痰平喘方治疗急性发作期儿童支气管哮喘的疗效明确且显著,可更快地控制哮喘,减轻或消除患儿的相关临床症状。
[Abstract]:Objective: To evaluate the efficacy of Huatan Pingchuan prescription in treating children with asthma in acute attack stage by comparing the related therapeutic indexes before and after treatment and between groups. To explore the curative effect of Huatan Pingchuan prescription in treating acute asthma in children with acute attack, and to lay a foundation for its clinical application. Methods: According to the study criteria, 60 children were randomly divided into treatment group and control group according to 1:1. The treatment group was treated with routine treatment of western medicine, Huatan Pingchuan prescription, once a day, while the control group was given routine treatment of western medicine. The course of treatment was 5 days in both groups. The symptoms and signs were observed before and after treatment, and the pulmonary function was detected. The difference of curative effect between the two groups was observed by using SPASS17.0 software, and the difference between the two groups was evaluated. Clinical effect of Huatan Pingchuan decoction on Acute attack of Children Asthma. Outcome: 1. After 5 days of treatment, both the treatment group and the control group could effectively improve the total clinical symptoms of the children. There was a significant difference between the two groups before and after treatment (P 0.05). The therapeutic effect of the treatment group in improving the total clinical symptoms was better than that in the control group (P 0.05). 2. There was significant difference between the treatment group and the control group in the change of the integral before and after the treatment of total symptoms of TCM, among which the change of the total symptom integral of the treatment group was greater than that of the control group, and the treatment group was superior to the control group in improving the symptoms, which had statistical significance. 3. There were significant differences in the clinical control and the onset time between the treatment group and the control group, among which the treatment group was better than the control group in the clinical control and onset time of the main symptoms of TCM, and had statistical significance (P 0.05). 4. After 5 days of treatment, both the treatment group and the control group were able to improve the pulmonary function effectively. There was a significant difference before and after treatment (P 0.05), and the treatment group was better than the control group in improving the lung function, which had statistical significance (P 0.05). Conclusion: The results showed that the curative effect of Huatan Pingchuan decoction on acute asthma in children was clear and remarkable. It could control asthma more quickly and relieve or eliminate the related clinical symptoms of children.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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