高剂量氨基酸和脂肪乳肠外营养对合并感染的早产患儿营养状况的影响研究

发布时间：2018-04-28 20:22

本文选题：早产合并感染 + 高剂量　；参考：《中华医院感染学杂志》2017年05期

【摘要】：目的探究不同肠外营养方式对其营养状况的临床实际影响,为早产合并感染患儿的临床研究实践提供借鉴和参考。方法选取2013年12月-2015年12月收治的早产合并感染患儿88例,根据肠外营养的方式不同将患儿分成高剂量组和低剂量组,各44例;以两组患儿的住院时间、恢复出生体质量时间、恢复出生体质量后体质量增长、肠外营养时间、出院体质量以及并发症发生情况等为观察指标。结果高剂量组患儿住院时间、恢复出生体质量时间和肠外营养时间分别为(12.43±2.51)d、(6.41±1.41)d和(7.41±1.11)d,明显少于低剂量组(14.98±3.49)d、(10.18±3.02)d和(10.29±3.20)d;高剂量组恢复出生体质量后体质量增长情况和出院体质量分别为(28.71±2.51)g/kg/d和(2066.43±244.32)g,明显高于低剂量组(17.02±4.32)g/kg/d和(1901.23±300.21)g;高剂量组和低剂量组患儿并发症发生率分别为0.00%和11.36%,差异有统计学意义(P0.05)。结论在给予患儿抗菌药物治疗的基础上,采用高剂量氨基酸和脂肪乳的肠外营养方式可以显著改善早产合并感染患儿的营养状况,提升临床的综合治疗效果。
[Abstract]:Objective to explore the clinical effects of different parenteral nutrition patterns on their nutritional status, and to provide reference for clinical study of children with preterm birth complicated with infection. Methods 88 children with preterm labor complicated with infection were selected from December 2013 to December 2015. According to the different parenteral nutrition, they were divided into high dose group and low dose group, 44 cases each. The growth of body mass, the time of parenteral nutrition, the mass of discharged body and the occurrence of complications were observed. Results the length of hospitalization in high dose group, The recovery time of birth weight and parenteral nutrition were 6.41 卤1.41d and 7.41 卤1.11d, respectively, which were significantly lower than those of low dose group (14.98 卤3.49d) 10.18 卤3.02d and 10.29 卤3.20d.The body weight increase and discharge body weight of high dose group were 28.71 卤2.51)g/kg/d and 2066.43 卤244.32g, respectively. The incidence of complications in high dose group and low dose group was 0.002% and 11.36%, respectively. The difference was statistically significant (P 0.05). Conclusion on the basis of antimicrobial therapy, parenteral nutrition with high dose of amino acid and fat emulsion can significantly improve the nutritional status of preterm infants with infection and improve the clinical comprehensive therapeutic effect.
【作者单位】：郑州大学附属南阳市中心医院儿科;
【基金】：河南省教育厅科学技术研究重点基金资助项目(132114712125)
【分类号】：R722.6

【参考文献】