182例重庆地区支气管扩张患儿临床特征及病因构成分析

发布时间：2018-05-02 07:14

本文选题：支气管扩张 + 临床特征　；参考：《临床儿科杂志》2017年08期

【摘要】：目的探讨儿童支气管扩张的常见病因及临床特征。方法回顾分析1991年至2015年5月在重庆医科大学附属儿童医院确诊为支气管扩张的住院患儿,以及中文数据库中,1990年至今病例数≥20例的支气管扩张患儿的病例资料。结果重庆地区支气管扩张182患儿例中男114例,女68例,中位年龄118个月。引起支气管扩张的前三位病因为感染后(29.7%)、原发性免疫缺陷病(7.7%)和支气管异物(7.7%)。慢性湿性咳嗽是儿童支气管扩张的主要表现,最常受累肺叶为左肺下叶、右肺中叶和右肺下叶。确诊需结合胸部CT。支气管扩张抗生素选择依据呼吸道分泌物培养,重庆地区最常见的分离菌为肺炎链球菌。另对重庆在内的中国7个城市共572例(男347例,女225例)支气管扩张儿童进行分析发现,前三位病因与重庆相同,所占比例分别为感染后45.5%、原发性免疫缺陷病7.3%和支气管异物5.6%。结论早期诊断、识别病因和综合管理利于儿童支气管扩张的预后。
[Abstract]:Objective to investigate the common causes and clinical features of bronchiectasis in children. Methods a retrospective analysis of the cases of bronchiectasis in children with bronchiectasis in the Affiliated Children's Hospital of Medical University Of Chongqing from 1991 to May 2015, and in the Chinese database, with more than 20 cases of bronchiectasis from 1990 to now. Results in Chongqing regional branch. In 182 cases of tracheal dilatation, there were 114 males and 68 females, with a median age of 118 months. The first three cases of bronchiectasis were caused by infection (29.7%), primary immunodeficiency disease (7.7%) and bronchial foreign body (7.7%). Chronic wet cough was the main manifestation of bronchiectasis in children. The most frequently involved lobes were left lower lobe, right middle lobe and right lung. The most common isolated bacteria in Chongqing area were Streptococcus pneumoniae in Chongqing, and 572 cases of bronchiectasis in 7 cities, including 347 men and 225 women in Chongqing, were analyzed. The first three causes were the same as those in Chongqing. Early diagnosis of primary immunodeficiency syndrome (7.3%) and bronchial foreign body 5.6%. (5.6%.) after infection, identification of etiology and comprehensive management were beneficial to the prognosis of bronchiectasis in children.

【作者单位】：重庆医科大学附属儿童医院呼吸中心儿童发育疾病研究教育部重点实验室儿童发育重大疾病国家国际科技合作基地儿科学重庆市重点实验室;
【基金】：国家临床重点专科项目(No.[2011]873)
【分类号】：R725.6

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