血乳酸及阴离子间隙在窒息新生儿中的应用价值

发布时间：2018-05-03 22:20

本文选题：窒息 + 新生儿　；参考：《中国现代医学杂志》2017年13期

【摘要】：目的探讨窒息新生儿血乳酸、阴离子间隙变化与其窒息程度的关系,指导临床治疗及判断预后。方法选择2014年1~12月海口市人民医院新生儿科窒息新生儿201例,纳入观察组;同期选择无窒息、病情稳定的新生儿205例,纳入对照组。分别在入院后1h检测血气指标及生化指标,按照窒息程度分组,比较各组间血气指标、血乳酸、AG值存在的差异。结果新生儿的性别、胎龄、体重等一般资料比较,差异无统计学意义(P0.05),该条件下,观察组窒息患儿血乳酸水平、AG值均高于对照组,差异均有统计学意义(P0.05),重度窒息患儿1 min Apgar、血乳酸水平和AG值高于轻度窒息患儿,差异有统计学意义(P0.05),但两组间患儿的p H值变化并不大(P0.05);治愈组和死亡组比较,两组患儿的胎龄、出生体重、p H值等指标,差异无统计学意义(P0.05),但死亡组患儿的血乳酸、AG值高于治愈组,且死亡组患者的1 min Apgar评分明显低于治愈组,差异均有统计学意义(P0.05)。结论血气乳酸水平和AG值在窒息患儿中表达高水平,有重要的诊断价值,并且在患儿的预后评估上也有一定的参考价值。
[Abstract]:Objective to investigate the relationship between the changes of blood lactic acid and anion gap and the degree of asphyxia in asphyxia neonates. Methods 201 neonates with neonatal asphyxia in Haikou people's Hospital from January to December 2014 were included in the observation group and 205 neonates without asphyxia and stable condition were selected as control group. Blood gas index and biochemical index were detected at 1 hour after admission. According to the degree of asphyxia, the differences of blood gas index and blood lactate AG were compared. Results there was no significant difference in sex, gestational age, body weight and other general data of newborns. Under this condition, the serum lactate level in the observation group was higher than that in the control group. The difference was statistically significant (P 0.05). The level of blood lactate and AG in severe asphyxia group was higher than that in mild asphyxia group (P 0.05). However, the pH value of the two groups was not changed significantly (P 0.05), and the difference between the cured group and the death group was not significant (P 0.05). There was no significant difference in gestational age, birth weight and pH between the two groups, but the serum lactate AG value in the death group was higher than that in the cured group, and the 1 min Apgar score in the dead group was significantly lower than that in the cured group (P 0.05). Conclusion the high level of blood gas lactate and AG in asphyxia children has important diagnostic value and also has certain reference value in the prognosis evaluation of children with asphyxia.
【作者单位】：海南省海口市人民医院检验科;
【分类号】：R722.12

【相似文献】