补脾益肺固表方治疗小儿反复呼吸道感染的临床研究

发布时间：2018-05-04 03:08

本文选题：补脾益肺固表方 + 小儿反复呼吸道感染　；参考：《南京中医药大学》2017年硕士论文

【摘要】：目的:本研究通过观察运用补脾益肺固表方治疗小儿反复呼吸道感染肺脾气虚证,并与对照组(口服匹多莫德分散片)比较,客观的评价补脾益肺固表方治疗复感儿的临床疗效。方法:本研究采用随机平行对照的方法,将符合纳入标准的60例复感儿作为受试者,分为治疗组、对照组各30例。治疗组予补脾益肺固表方内服,对照组予匹多莫德分散片口服,两组分别治疗2个月。随访6个月,最后对统计数据进行分析,客观评价两种方案治疗后的临床疗效。结果:(1)在证候疗效方面,治疗组总有效率为90.00%,高于对照组(76.67%),差异具有统计学意义(P0.05);在疾病疗效方面,治疗组总有效率为93.33%;高于对照组(86.67%),差异具有统计学意义(P0.05)。(2)在中医证候积分评价方面:治疗前2个月,两组患儿各症状积分改善不明显,对比无统计学差异(P0.05);在治疗后随访的第3个月,治疗组主症积分改善较前差异有统计学意义,且同等时间在改善多汗、恶风寒等症状方面与对照组比较有统计学差异;治疗6个月后主症指标(面色、懒言、饮食)、次症指标(精神、睡眠)等积分两组间比较有统计学差异(P0.05),其中多汗、懒言、大便异常等症状积分两组间比较,有显著统计学意义(P0.01)。(3)在改善病程、病种、发病次数等方面,两组比较差异具有统计学差异(P0.05);与治疗前比较,两组均可改善上呼吸道感染次数,差异有统计学意义(P0.05)。结论:补脾益肺固表方总体疗效较好,是治疗小儿反复呼吸道感染的有效方法,可明显减少呼吸道感染次数,也可以改善患儿临床症状,可应用于临床,以进一步发挥中医药治疗小儿疾病的特色与优势。
[Abstract]:Objective: to observe the treatment of deficiency of lung and spleen qi in children with recurrent respiratory tract infection by using the prescription of tonifying the spleen and supplementing the lung, and compare it with that of the control group (oral pidomod dispersible tablets). Objective to evaluate the clinical effect of tonifying the spleen and supplementing the lung to treat the children with complex sensation. Methods: in this study, 60 children with complex sensation were divided into treatment group (n = 30) and control group (n = 30). The treatment group was given internal administration of Bupi Yifei Gubiao recipe, the control group was treated with Pidomod dispersible tablets for 2 months respectively. Follow-up for 6 months. Finally, the statistical data were analyzed to evaluate the clinical efficacy of the two regimens. Results the total effective rate of the treatment group was 90.00g, which was higher than that of the control group 76.677.The difference was statistically significant (P 0.05), and the curative effect of the treatment group was higher than that of the control group (P < 0.05). The total effective rate of the treatment group was 93.33, which was higher than that of the control group (86.67%). The difference was statistically significant (P 0.05). In the evaluation of TCM syndromes, two months before treatment, there was no significant improvement in the symptom scores of the two groups. In the third month of follow-up, the improvement of the main symptom score in the treatment group was statistically significant compared with the control group, and there was statistical difference between the treatment group and the control group in improving hyperhidrosis and wind-cold symptoms at the same time. After 6 months of treatment, there were significant differences between the two groups in the score of the main symptoms (facial appearance, lazy speech, diet, secondary symptom index (spirit, sleep) and so on). There was a significant difference between the two groups in the score of hyperhidrosis, lazy speech, abnormal stool and other symptoms, among them, there was a significant difference between the two groups in the score of symptoms such as excessive sweating, lazy speech and abnormal stool. There was significant statistical difference between the two groups in improving the course of disease, disease species, incidence times and so on. Compared with before treatment, the two groups could improve the times of upper respiratory tract infection, and the difference was statistically significant. Conclusion: the prescription of tonifying spleen and invigorating the lung is an effective method for the treatment of recurrent respiratory tract infection in children. It can significantly reduce the number of respiratory tract infections, improve the clinical symptoms of children, and can be used in clinical practice. In order to further give play to the characteristics and advantages of traditional Chinese medicine in the treatment of pediatric diseases.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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