无创心指数检测在评价新生儿先天性心脏病合并心力衰竭的临床应用价值

发布时间：2018-05-04 07:21

本文选题：电子心力测量法 + 心指数　；参考：《临床儿科杂志》2017年10期

【摘要】：目的探讨电子心力测量法心指数(CI)监测在评价新生儿先天性心脏病合并心力衰竭中的临床应用价值。方法选取2016年3月1日—2016年12月30日新生儿科收治的60例先天心脏病患儿,根据改良Ross心衰评分标准,分为重度组(n=11)、中度组(n=15)、轻度组(n=34)及无心衰组(n=10);应用电子心力测量法测量各组患儿的CI,心脏超声测量患儿左室射血分数(LVEF)、肺动脉压力(PAP),静脉采血检测氨基末端B型脑钠肽前体(NT-pro BNP)。结果重度组主要为2周龄以下患儿,轻、中度组大于2周龄患儿为主。各组间CI、LVEF、NT-pro BNP和PAP的差异均有统计学意义,其中重度组CI和LVEF值最低,其次为中度、轻度,无心衰组最高;重度组NT-pro BNP和PAP值最高,其次为中度、轻度,无心衰组最低。相关分析显示,CI与LVEF呈显著正相关(r=0.845,P0.001),CI与NT-pro BNP呈显著负相关(r=0.886,P0.001);CI与PAP呈弱的负相关(r=0.595,P0.001)。结论 CI在一定程度上反应心衰程度,有一定的临床价值。
[Abstract]:Objective to explore the clinical value of cardiac index (CI) monitoring in evaluating neonatal congenital heart disease with heart failure. Methods 60 children with congenital heart disease admitted from March 1, 2016 to December 30, 2016 were selected to be divided into severe group (n=11) and moderate group (n=15) according to the improved Ross heart failure score standard. Light group (n=34) and heart failure group (n=10) were used to measure CI of children in each group by electronic cardiac force measurement, left ventricular ejection fraction (LVEF), pulmonary artery pressure (PAP), and B type natriuretic peptide precursor (NT-pro BNP) of amino terminal group (NT-pro BNP) were measured by echocardiography. The results were mainly in children under 2 weeks of age, light and moderate groups were more than 2 weeks old. Main. The differences of CI, LVEF, NT-pro BNP and PAP were statistically significant, and CI and LVEF in severe group were the lowest, followed by moderate, mild, and no heart failure group, and NT-pro BNP and PAP were the highest in severe group, followed by moderate, mild, and no heart failure. There was a significant negative correlation (r=0.886, P0.001); CI and PAP showed a weak negative correlation (r=0.595, P0.001). Conclusion CI has a certain degree of response to the degree of heart failure, and has certain clinical value.

【作者单位】：湖南省人民医院儿童医学中心儿童心血管科;湖南省人民医院儿童医学中心新生儿科;湖南省人民医院超声科;湖南师范大学医学院;
【基金】：湖南省自然科学基金(No.13JJ5019)
【分类号】：R722.1

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