内蒙古中西部儿童孤独症谱系障碍患病情况及影响因素

发布时间：2018-05-04 07:52

本文选题：孤独性障碍 + 患病率　；参考：《中国学校卫生》2017年12期

【摘要】：目的了解内蒙古中西部儿童孤独症谱系障碍(autism spectrum disorder,ASD)的患病情况及相关影响因素,为完善国内ASD整体流行病学的调查提供数据支持。方法 2016年9月至2017年6月选择内蒙古中西部包头市、乌海市、巴彦淖尔市3个具有代表性的盟市,采用随机整群抽样的方法,共抽取25所小学及幼儿园的3~14岁儿童16 784名,由主要抚养人填写克氏孤独症行为量表;初筛阳性者再填写孤独症行为检测量表,并结合量表得分由临床专业人员根据美国精神障碍诊断与统计手册第五版诊断标准确诊ASD。结果共检出确诊ASD儿童54例,总体患病率为0.32%(54/16 784),其中男生41例,女生13例。ASD组与正常儿童组性别、家庭经济情况、不良习惯、语言发育水平、父母内向、主要教育方式分布差异均有统计学意义(χ~2值分别为12.344,18.257,22.311,45.959,15.683,35.594,P值均0.05),两组在是否存在新生儿疾病分布上差异有统计学意义(χ~2=12.214,P0.05)。Logistic回归分析显示,打骂教育、语言发育落后、父母内向、患有新生儿疾病是ASD发生的危险因素(OR值分别为1.603,2.413,2.818,2.365,P值均0.05)。结论内蒙古中西部儿童孤独症谱系障碍患病率与国内报道基本一致,低于国外水平。采取改变父母教育方式、调整父母性格、关注儿童早期语言发育水平、避免新生儿期疾病等措施可能会预防儿童ASD的发生。
[Abstract]:Objective to investigate the prevalence and related factors of autism in children with autism spectrum disorders in central and western Inner Mongolia, and to provide data support for improving the overall epidemiological investigation of ASD in China. Methods from September 2016 to June 2017, 16 784 children aged 14 years old from 25 primary schools and kindergartens were selected from Baotou City, Wuhai City and Bayannur City, Inner Mongolia, from September 2016 to June 2017. The primary dependents filled out the Kirschner Autism behavior scale, the positive individuals filled in the Autism behavior Test scale, and the clinical professionals confirmed ASD according to the fifth edition of American Diagnostic and Statistical Manual for Mental Disorder. Results A total of 54 children with ASD were diagnosed. The overall prevalence rate was 0.3254 / 16 784%. Among them, 41 cases were male, 13 cases were female, gender, family economic condition, bad habits, language development level, introversion of parents, 13 cases of ASD group and normal children group. There were statistically significant differences in the distribution of major educational patterns (蠂 ~ 2 = 12.344 / 18.257U 22.3119 / 15.683 ~ 35.594p = 0.05P, respectively). There was a significant difference in the distribution of neonatal diseases between the two groups (蠂 ~ (2 +) 12.214p 0.05.Logistic regression analysis showed that scolding education, language development was backward, parents were introverted, and there was no significant difference between the two groups in the distribution of neonatal diseases. The OR value of neonatal disease as a risk factor of ASD was 1.603U 2.4132.8181.365 (P < 0.05), respectively. Conclusion the prevalence rate of autism spectrum disorders in children in central and western Inner Mongolia is consistent with the reports in China and is lower than that in foreign countries. Some measures, such as changing parents' education, adjusting parents' character, paying attention to children's early language development and avoiding neonatal diseases, may prevent the occurrence of ASD in children.
【作者单位】：内蒙古科技大学包头医学院公共卫生学院;中山大学公共卫生学院;巴彦淖尔市疾病预防控制中心;
【基金】：国家自然科学基金项目(81560532) 包头医学院科学研究基金项目(BYJJ-QM201646)
【分类号】：R749.94

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