NCPAP联合小剂量多巴胺用于小儿重症毛细支气管炎临床效果观察

发布时间：2018-05-07 01:11

本文选题：毛细支气管炎 + 鼻塞式持续气道正压通气　；参考：《山东医药》2017年20期

【摘要】：目的探讨鼻塞式持续气道正压通气(NCPAP)联合小剂量多巴胺治疗重症毛细支气管炎患儿的临床疗效。方法选择重症毛细支气管炎患儿200例,随机分为对照组和观察组各100例。在常规治疗的基础上,对照组给予面罩吸氧;观察组给予NCPAP辅助通气并联合小剂量多巴胺[3~5μg/(kg·min)]微量注射泵静滴,滴注多巴胺后给予呋塞米利尿,3天为一个疗程。分别于治疗前及治疗6、12、24 h检测PaO_2、PaCO_2及pH,评价临床疗效,比较两组症状、体征消失时间及并发症发生率。结果两组治疗后各时点PaO_2、pH均逐渐升高,PaCO_2均逐渐降低;但观察组各项指标改善程度均大于对照组;组间及组内比较P0.05或0.01。观察组呼吸、心率恢复正常时间及咳嗽、喘憋、肺部罗音消失时间均较对照组缩短(P0.05或0.01);观察组总有效率为85.0%,对照组为70.0%,两组比较P0.05;观察组并发症发生率为27.0%,对照组为35.0%,两组比较P0.05。结论 NCPAP辅助呼吸联合小剂量多巴胺用于小儿重症毛细支气管炎治疗效果好,且较为安全。
[Abstract]:Objective to investigate the clinical effect of nasal continuous positive airway pressure ventilation (NCPAP) combined with low dose dopamine in the treatment of children with severe bronchiolitis. Methods 200 children with severe bronchiolitis were randomly divided into control group (n = 100) and observation group (n = 100). On the basis of routine treatment, the control group was given oxygen inhalation by mask, and the observation group was given NCPAP assisted ventilation combined with small dose of dopamine [35 渭 g/(kg min] microinjection pump, and then given furosemide diuretic for 3 days as a course of treatment. PaO-2 Paco _ 2 and pH were measured before treatment and 612h after treatment, to evaluate the clinical efficacy and to compare the symptoms, the time of disappearance of signs and the incidence of complications between the two groups. Results Paco _ 2 increased gradually in both groups at all time points after treatment, but the improvement degree of Paco _ 2 in observation group was higher than that in control group. In the observation group, breathing, heart rate returning to normal time, cough, wheezing, suffocating, The total effective rate of observation group was 85.0 and that of control group was 70.05.The incidence of complications in observation group was 27.0 and that in control group was 35.0.The total effective rate in observation group was 85.0 and that in control group was 70.05.The incidence of complications in observation group was 27.0 and that in control group was 35.0. Conclusion NCPAP assisted respiration combined with low dose dopamine is effective and safe in the treatment of severe bronchiolitis in children.
【作者单位】：哈励逊国际和平医院;
【分类号】：R725.6

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