夫西地酸对新生儿和小婴儿血清胆红素水平的影响

发布时间：2018-05-07 15:17

  本文选题：夫西地酸 + 胆红素　； 参考：《中国感染与化疗杂志》2017年03期

【摘要】：目的探讨新生儿和小婴儿应用夫西地酸后血清胆红素的变化。方法对2012-2014年青岛市妇女儿童医院应用夫西地酸的半岁以下患儿用药前后的血清胆红素等指标进行回顾性分析,比较用药前后的血清胆红素变化情况。结果所有138例应用夫西地酸治疗的患儿,治疗后均未出现新发黄疸或原有黄疸加重的情况;其中64例用药前后检测了血生化指标,治疗前后白蛋白、丙氨酸转氨酶、天冬氨酸转氨酶等均无显著差异,治疗后的间接胆红素与总胆红素比值(Ibil/Tbil)比用药前下降了约8%。结论该系列应用夫西地酸的患儿中未见该药对血清胆红素水平的明显影响。
[Abstract]:Objective to investigate the changes of serum bilirubin in newborns and small infants. Methods the indexes of serum bilirubin before and after treatment were analyzed retrospectively and the changes of serum bilirubin in Qingdao Women and Children Hospital from 2012 to 2014 were compared. Results none of 138 children treated with fossillic acid had new jaundice or aggravation of the original jaundice after treatment, and 64 of them detected serum biochemical indexes, albumin and alanine aminotransferase before and after treatment. The ratio of indirect bilirubin to total bilirubin decreased by about 8% compared with that before treatment. Conclusion the serum bilirubin level was not significantly affected by this series of children with fusidic acid.
【作者单位】： 青岛市妇女儿童医院药剂科;
【分类号】：R725.1
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本文编号：1857430