健胃宝冲剂治疗小儿脾虚型厌食症的临床研究

发布时间：2018-05-10 11:22

  本文选题：小儿厌食症 + 脾虚型　； 参考：《南京中医药大学》2012年硕士论文

【摘要】：目的：评价健胃宝冲剂治疗小儿脾虚型厌食症的有效性和安全性。 方法：选取2011年03月至2011年10月间在盐城市中医院治疗脾虚型厌食症患儿60例,按照随机对照原则分为治疗组和对照组。中医治疗组30例采用健胃宝冲剂治疗,主要药物组成为苍术,白术,山楂,鸡内金,陈皮,太子参；对照组30例采用西药小儿复方四维亚铁散。 结果：治疗组痊愈13例,占43.3%,显效11例,占36.7%,进步5例,占16.7%,无效1例,占3.3%,总有效率96.7%；对照组痊愈7例,占33.3%,显效6例,占28.3%,进步9例,占23.3%,无效8例,占15.8%,总有效率84.2%；两组比较,差异有显著统计学意义(P0.05),两组治疗后患儿血红蛋白变化量比较,差异有显著统计学意义(P0.05),两组在主症积分比较有显著差异(P0.05),次症积分改善比较无明显差异,另外两组患儿治疗期间均没有出现严重不良反应。 结论：健胃宝冲剂治疗脾虚型厌食症疗效显著,安全性好,在临床上具有进一步推广应用的价值,但对其远期疗效还需要进一步研究。
[Abstract]:Objective: to evaluate the efficacy and safety of Jianwei Bao granule in treating anorexia of spleen deficiency in children. Methods: from March 2011 to October 2011, 60 children with anorexia due to spleen deficiency were divided into treatment group and control group according to the principle of random control. The traditional Chinese medicine treatment group (30 cases) was treated with Jianwei Bao granule, the main drug composition was Atractylodes, Hawthorn, Chicken Inner Gold, Old Peel, Radix Pseudostellariae, and the control group (30 cases) was treated with western medicine compound Siwei ferrous powder. Results: in the treatment group, 13 cases were cured (43.3%), 11 cases were markedly effective (36.7%), 5 cases were improved (16.7%), 1 case was ineffective (3.3%), and the total effective rate was 96.7.The control group (7 cases) was cured, 33.3 cases (33.3%), 6 cases (28.3 cases), 9 cases of progress (23.3%), and 8 cases of ineffectiveness. The total effective rate was 84.2%, and the difference between the two groups was statistically significant (P 0.05). The difference was statistically significant (P 0.05). There was significant difference in the main symptom score between the two groups. There was no significant difference in the improvement of the secondary symptom score. There was no serious adverse reaction during the treatment of the other two groups. Conclusion: Jianwei Bao granule is effective and safe in treating anorexia of spleen deficiency type.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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