早产儿维生素D水平与肺部疾病的关系

发布时间：2018-05-25 08:33

  本文选题：-羟维生素D + 新生儿呼吸窘迫综合征　； 参考：《临床儿科杂志》2017年12期

【摘要】：目的分析早产儿出生时血清25-羟维生素D[25(OH)D]水平与肺部疾病的关系。方法选取2015年1月至2016年12月入住NICU的早产儿,收集其临床资料及血清25(OH)D检测结果 ;并根据平均血清25(OH)D水平将早产儿分为低维生素D组和高维生素D组,分析比较两组肺部疾病发生的差异。结果共纳入早产儿115例,平均胎龄为(29.9±1.9)周,平均血清25(OH)D水平为(37.1±16.6)nmol/L。维生素D缺乏[25(OH)D50 nmol/L]、不足[25(OH)D在50~74.9 nmol/L]和正常[25(OH)D≥75 nmol/L]的比率分别为71.3%、17.4%和11.3%。低维生素D组的持续气道正压通气、氧疗时间、新生儿呼吸窘迫综合征(RDS)和支气管肺发育不良(BPD)发生率以及住院天数均显著高于高维生素D组,差异有统计学意义(P均0.05)。结论早产儿低维生素D水平可能增加RDS、BPD的发生率,并延长住院时间。
[Abstract]:Objective to analyze the relationship between serum 25-hydroxyvitamin D [25(OH)D] and pulmonary diseases in premature infants. Methods premature infants admitted to NICU from January 2015 to December 2016 were selected and their clinical data and serum 25(OH)D test results were collected, and the preterm infants were divided into low vitamin D group and high vitamin D group according to the average serum 25(OH)D level. The difference between two groups of lung diseases was analyzed and compared. Results 115 premature infants were included, the average gestational age was 29.9 卤1.9 weeks, and the average serum 25(OH)D level was 37.1 卤16.6nmol / L. The ratios of vitamin D deficiency [25(OH)D50 nmol/L], deficiency [25(OH)D at 50,74.9 nmol/L] and normal [25(OH)D 鈮，

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