心脏外科ICU患儿多药耐药菌感染的综合干预措施研究

发布时间：2018-05-29 04:50

本文选题：医院感染 + 多药耐药菌　；参考：《中华医院感染学杂志》2017年18期

【摘要】：目的分析心脏外科ICU患儿多药耐药菌(MDRO)聚集事件的控制过程,对医院感染耐药菌株聚集综合干预策略进行评价。方法前瞻性干预管理2014年1月-2016年12月小儿心外监护2起多药耐药菌聚集事件,对照2008年1月-2013年12月4起聚集事件,对多药耐药菌预警时机、隔离措施执行情况、手卫生依从性、防护用品使用、常规环境消毒效果、抗菌药物管理等一系列干预策略,进行综合评价。结果综合干预后,耐药菌聚集事件平均持续时间由28.25d缩短为14.50d,感染患儿耐药菌清除率由41.18%上升为72.73%,干预前后比较差异有统计学意义(P0.05);实施综合干预措施后,临床24h内隔离措施执行率、医务人员手卫生依从性、环境消毒达标率均明显提高(P0.05)。结论 MDRO综合干预措施可以明显缩短耐药菌聚集事件的控制时间、提高感染患儿耐药菌清除率。
[Abstract]:Objective to analyze the control process of multidrug resistant bacteria (MDR) aggregation events in children with ICU in cardiac surgery, and to evaluate the comprehensive intervention strategy of drug resistant strains in nosocomial infection (Nosocomial infection). Methods from January 2014 to December 2016, two multidrug resistant bacteria (MDR) aggregation events were managed by prospective intervention, compared with 4 events from January 2008 to December 2013, the timing of early warning of MDR bacteria and the implementation of isolation measures. A series of intervention strategies, such as hand hygiene compliance, protective equipment use, routine environmental disinfection effect, antimicrobial drug management, were comprehensively evaluated. Results after comprehensive intervention, the average duration of drug-resistant bacteria aggregation events was shortened from 28.25 days to 14.50 days, and the clearance rate of drug-resistant bacteria increased from 41.18% to 72.73. There was a significant difference between before and after intervention (P 0.05). The rate of carrying out isolation measures in 24 hours, the compliance of hand hygiene of medical personnel, and the rate of environmental disinfection reaching the standard were significantly improved (P 0.05). Conclusion the comprehensive intervention of MDRO can significantly shorten the control time of drug resistant bacteria aggregation events and improve the clearance rate of drug resistant bacteria in infective children.
【作者单位】：首都医科大学附属北京安贞医院医院感染管理办公室;首都医科大学附属北京安贞医院小儿心脏外科中心;
【基金】：国家自然科学基金资助项目(81371443)
【分类号】：R726.5

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