手足口病2号方治疗手足口病热毒内蕴证临床研究

发布时间：2018-06-02 08:13

本文选题：手足口病 + 重症　；参考：《山东中医药大学》2012年硕士论文

【摘要】：目的：通过临床观察评价手足口病2号方对小儿手足口病重症的有效性和安全性，探讨中医药防治手足口病的作用机制，为进一步临床应用提供依据。方法：将符合纳入标准的患儿分为治疗组和对照组。治疗组口服手足口病2号方，对照组口服利巴韦林配合干扰素肌注，疗程6天，观察两组用药前后的症状、体征及理化指标的变化，，观察结束后，对各项指标进行统计学处理。结果：治疗组在总有效率、退热起效时间方面明显优于对照组；治疗组在愈显率、改善咳嗽等次要症状方面也优于对照组，且未发现明显毒副作用。结论：手足口病2号方治疗小儿手足口病重症疗效显著，能快速改善症状，缩短病程且服用方便，安全。
[Abstract]:Objective: to evaluate the efficacy and safety of HFMD No. 2 in children with HFMD by clinical observation, and to explore the mechanism of TCM in the prevention and treatment of HFMD in order to provide the basis for further clinical application. Methods: the children who met the inclusion criteria were divided into treatment group and control group. The treatment group took the second prescription of hand, foot and mouth disease and the control group took ribavirin plus interferon intramuscular injection for 6 days. The changes of symptoms, signs and physical and chemical indexes before and after the treatment were observed. After observation, the indexes were treated statistically. Results: the total effective rate and antipyretic onset time of the treatment group were significantly better than that of the control group, and the treatment group was also superior to the control group in the recovery rate and the improvement of cough and other minor symptoms, and no obvious toxic side effects were found in the treatment group. Conclusion: Hand-foot-mouth disease prescription No. 2 is effective in treating severe hand foot and mouth disease in children. It can quickly improve symptoms, shorten the course of disease, and be convenient and safe to take.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R272

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