磁敏感加权成像对新生儿缺氧缺血性脑病磁共振常规序列分度的评价

发布时间：2018-06-15 12:41

本文选题：缺氧缺血性脑病 + 新生儿　；参考：《临床放射学杂志》2017年11期

【摘要】：目的探讨磁敏感成像(SWI)序列对新生儿缺氧缺血性脑病(HIE)磁共振常规序列分度的评价。方法回顾性分析86例经临床确诊HIE患儿的常规MRI及SWI序列图像,按照常规MRI表现将其分为轻、中、重度三组,再利用SWI序列观察出血灶的形态、分布、数目及静脉扩张的程度、范围,对三组患儿颅内出血灶、静脉扩张检出率进行统计学分析。结果 86例患儿采用SWI检出的颅内出血灶57例,共97处,检出脑内深部静脉及皮质静脉扩张49例,颅内出血合并静脉扩张38例。以MRI平扫分度的三组HIE患儿颅内出血检出率、静脉扩张及颅内出血合并静脉扩张检出率有统计学差异(P分别为0.011,0.013,0.035),且颅内出血、脑内静脉扩张、颅内出血合并脑内静脉扩张的检出率在重度组比例最高,轻度组最低。结论轻度组SWI序列检出颅内出血及静脉扩张率明显低于中度组和重度组,所以通过SWI序列可更准确地反映HIE患儿的病情轻重程度。
[Abstract]:Objective to evaluate the conventional magnetic resonance (Mr) grading of neonatal hypoxic-ischemic encephalopathy (HIE) by magnetic sensitive imaging (MRI). Methods the routine MRI and SWI images of 86 children with clinically diagnosed HIE were retrospectively analyzed. According to the conventional MRI findings, they were divided into three groups: mild, moderate and severe. The morphology, distribution, number and degree of venous dilatation were observed by SWI sequence. Range, the detection rate of intracranial hemorrhage and venous dilatation in three groups were analyzed statistically. Results there were 57 intracranial hemorrhage foci (97 sites) detected by SWI in 86 cases, 49 cases of deep cerebral vein and cortical vein dilatation, 38 cases of intracranial hemorrhage combined with vein dilatation. The detectable rates of intracranial hemorrhage, venous dilatation and intracranial hemorrhage combined with venous dilatation were 0.011 ~ 0.013 ~ 0.035, respectively, and intracranial hemorrhage and intracerebral vein dilatation were found in the three groups of HIE. The detection rate of intracranial hemorrhage with intracerebral vein dilatation was the highest in the severe group and the lowest in the mild group. Conclusion the rate of intracranial hemorrhage and venous dilatation detected by SWI sequence in mild group is significantly lower than that in moderate group and severe group, so SWI sequence can more accurately reflect the severity of HIE.
【作者单位】：南京医科大学附属儿童医院放射科;
【基金】：南京市科技发展项目基金支持(编号:YKK14117)
【分类号】：R445.2;R742

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