脐血CD64在新生儿早期败血症中的诊断价值

发布时间：2018-06-17 11:23

本文选题：中性粒细胞CD + 新生儿　；参考：《中国现代医学杂志》2017年04期

【摘要】：目的探讨中性粒细胞CD64在新生儿早期败血症中的临床诊断价值。方法选取2015年6~11月于深圳市龙华新区中心医院产科产检并分娩的50例新生儿,分为感染组(n=18)和对照组(n=32),检测两组出生时脐静脉血、0~12 h外周静脉血CD64水平和血培养,并通过分析两组相同或不同时间CD64的变化,探讨其对新生儿早发型败血症的诊断价值。结果感染组脐静脉血CD64水平高于对照组,差异有统计学意义(t=-3.15,P=0.010);感染组0~12 h外周血CD64较对照组升高,差异有统计学意义(t=-3.35,P=0.004);感染组脐血与0~12 h外周静脉血之间CD64比较,差异无统计学意义(t=-0.507,P=0.623)。结论中性粒细胞CD64对新生儿败血症的早期诊断具有一定的临床应用价值,脐血中性粒细胞CD64可作为宫内细菌感染、早发型败血症的诊断指标。
[Abstract]:Objective to evaluate the clinical value of neutrophil CD64 in early neonatal septicemia. Methods from June to November, 2015, 50 newborns were divided into infected group (n = 18) and control group (n = 32). The peripheral venous blood CD64 level and blood culture were measured at 12 h after birth. By analyzing the changes of CD64 in two groups at the same or different time, the diagnostic value of CD64 in neonatal premature septicemia was discussed. Results the level of CD64 in umbilical vein blood in infected group was higher than that in control group, the difference was statistically significant, the CD64 level in peripheral blood of infected group was higher than that in control group at 12 h after infection, the difference was statistically significant, and the CD64 level in umbilical cord blood and peripheral venous blood in infected group was higher than that in control group at 12 h, and the level of CD64 in infected group was higher than that in peripheral venous blood of 0 ~ 12 h, and the level of CD64 in infected group was significantly higher than that in control group. The difference was not statistically significant. Conclusion the neutrophil CD64 has a certain clinical value in the early diagnosis of neonatal septicemia. Umbilical cord blood neutrophil CD64 can be used as a diagnostic index of intrauterine bacterial infection and early septicemia.
【作者单位】：广东省深圳市龙华新区中心医院新生儿科;
【基金】：深圳市科技创新委员会基础研究项目(No:JCYJ20150402140827354)
【分类号】：R722.131

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